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Project Management Office in Clinical Research Projects [PDF]
Context: Clinical research is an interdisciplinary project which has been given a high priority by health organizations. Because of its complexity and importance, most of health system authorities have supported the using of project management knowledge and skills in performance of health and clinical researches.
Hamid Reza Aghayan +6 more
openaire +1 more source
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook +6 more
wiley +1 more source
Background Globally, according to the World Health Organization (WHO) 2023 report, more than 14.3 million children in low- and middle-income countries, primarily in Africa and South-East Asia, are not receiving any vaccinations.
Gashaw Andargie Biks +9 more
doaj +1 more source
Increasing attention is being given to reach children who fail to receive routine vaccinations, commonly designated as zero-dose children. A comprehensive understanding of the supply- and demand-side barriers is essential to inform zero-dose strategies ...
Gashaw Andargie Biks +12 more
doaj +1 more source
The article deals with current issues of increasing the efficiency of management of the Fund of National Welfare investments in the implementation of major infrastructure projects of national importance.
Alina Yu. Struk
doaj +1 more source
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási +14 more
wiley +1 more source
The Model of Master’s Degree Program in Product Design Engineering
The paper presents the model of Master’s Degree Program in Product Design Engineering implemented for training engineers majoring in “Innovation shipbuilding”. The program is being rolled out as a pilot project since 2017 on the basis of the Institute of
Vladimir D. Nechaev +2 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Exploration and Analysis of Hidden Fault Identification Methods in the Ordos Basin
Recently, in order to strengthen the exploration and development of oil and gas resources in the Ordos Basin, seismic exploration has changed from a two-dimensional to a three-dimensional (3D) scale.
Pengfei LI +6 more
doaj +1 more source

