Results 111 to 120 of about 5,448,477 (310)

project : perform [PDF]

open access: yes, 2008
Publication on student work by First Year Students, and essays by course tutors, School of Architecture and Landscape, Faculty of Art, Design and Architecture, Kingston University London.
openaire  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Conceptual modelling: framework, principles, and future research [PDF]

open access: yes, 2007
The conceptual modelling task in a simulation project is very important and yet is still generally regarded as more of an art than a science. The meaning and nature of conceptual modelling are discussed and a framework set out.
Brooks, R J
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Innovation Project Performance Measurement: Selected Shortcomings

open access: yesLittera Scripta, 2015
This paper presents an overview of studies that describe the emergence of innovation project performance measurement. It is dedicated to the issue of economic indicators and focuses on the metrics that can be employed to evaluate a single innovation ...
Ondřej Žižlavský
doaj  

A framework to evaluate the impact of ICT usage on collaborative product development performance in manufacturing firms : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Engineering at Massey University, Auckland, New Zealand [PDF]

open access: yes, 2017
Manufacturers are increasingly adopting collaborative product development (CPD) to achieve competitive advantage through joint synergies. Information and communication technology (ICT) is the major enabler of communication, collaboration, product ...
Silva, C W Chathurani
core  

The contronymity of project accounting for performing the relevance of project outcomes

open access: yesAccounting, Auditing & Accountability Journal
PurposeThis paper aims to advance recent literature on the performativity of accounting by examining how project accounting affects a project organization’s ability to deliver a relevant project outcome, such as a product or a building, for a receiving client organization.Design/methodology/approachThe paper draws on a longitudinal case study of a 41.4-
Tim Neerup Themsen   +2 more
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

WHAT DO WE MEAN BY INNOVATION IN HEALTHCARE?

open access: yesEuropean Medical Journal Innovations, 2017
Just as in other modern industries, the term ‘innovation’ in healthcare has become associated with new developments in the field that allow for improvements in solving problems, in this instance, healthcare problems.
Leighann Kimble, M. Rashad Massoud
doaj  

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