Results 201 to 210 of about 1,342,681 (265)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Enhancing diabetes risk stratification through natural language processing: a multimodal data integration approach. [PDF]

Front Public Health
Lu Y, Li T, Ge L, Wei Y, Li Y, Huang S, Jiang T, Chen Y, Xiang Z.   +8 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Performance Measurement for Surgery at National Level in China. [PDF]

Health Care Sci
Zhang T, Zhuang Q, Liu W, Liu Y, Zhang B, Zhang M, Zhang X, Li L, Liu J, Ye Z.   +9 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Platelet-related parameters at initial diagnosis for predicting the risk of chronicity in children with newly diagnosed immune thrombocytopenia. [PDF]

Front Pediatr
Zheng S, Liang J, Jiang W, Han R, Guo X.
europepmc   +1 more source

Improving Breast Cancer Screening Coverage in Primary Healthcare: A Quality-Improvement Study (2023-2025). [PDF]

Cureus
AlAwadh SA, AlShammari RZ, AlJohi HA, Aseeri RM, AlOhali FT, Alghamdi AM, AlAhmari N, Alharthi S.   +7 more
europepmc   +1 more source

Integration of Transcriptomics With Interpretable Artificial Intelligence for Identifying Molecular Signatures of Physiological Stress in Sleep Deprivation. [PDF]

J Cell Mol Med
Wang K, Zong Q, Wang C, Wang P, Shuai Z, Wu M, Peng Y, Zhou J, Shuai J, Ye F, Wu A, Zheng Y.   +11 more
europepmc   +1 more source

User Acceptance of Remote Care Assist, a Telecare System for Home Care Among Care and Nursing Staff: Cross-Sectional Pilot Study. [PDF]

JMIR Rehabil Assist Technol
Ebner F, Schneider U, Schneider C, Trukeschitz B.   +3 more
europepmc   +1 more source