Results 111 to 120 of about 15,188,723 (294)

Unveiling opportunities and challenges for a circular approach to macaúba biorefining: a technological roadmap

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract The macaúba fruit, native to tropical and subtropical regions, has received considerable attention in recent years as a promising raw material for the production of advanced biofuels in Brazil. However, the development of large‐scale biomass requires overcoming significant challenges, such as designing circular biorefineries.
Fábio de A. Oroski   +3 more
wiley   +1 more source

Portfolio optimization when risk factors are conditionally varying and heavy tailed [PDF]

open access: yes, 2006
Assumptions about the dynamic and distributional behavior of risk factors are crucial for the construction of optimal portfolios and for risk assessment.
Hartz, Christoph   +2 more
core  

A Model for R&D Project Portfolio Selection and Development in LCSI Enterprises [PDF]

open access: yesچشم‌انداز مدیریت صنعتی, 2018
All Organization face with important issues like objectives, constraints, priorities, policies, opportunities and threats that should be considered in all the key decisions.
Reza Nooraei Baydokht   +2 more
doaj  

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló   +5 more
wiley   +1 more source

On Insurer Portfolio Optimization. An Underwriting Risk Model [PDF]

open access: yes
Multicriteria portfolio optimization started with the Markowitz mean-variance model (Markowitz 1952, 1959). This model assumes that the goal of an average or standard investor is to maximize the unknown return on investment.
Preda, Vasile, Ciumara, Roxana
core  

STRATEGICALLY ORIENTED PROJECT MANAGEMENT OF THE DEVELOPMENT OF TERRITORIAL COMMUNITIES IN CONDITIONS OF UNCERTAINTY AND RESOURCE CONSTRAINTS

open access: yesПублічне управління та регіональний розвиток
The article examines the theoretical, methodological and applied principles of strategically oriented project management of the development of territorial communities in conditions of uncertainty, indeterminacy of the external environment and resource ...
Yaroslav Zhovnirchyk
doaj   +1 more source

Through the lens of marketing authorization holders: experience in use of real‐world data and real‐world evidence in drug development and regulatory submissions in EU

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to assess the general and product‐specific experiences of MAHs use of RWD/RWE in medicines development and in their regulatory submissions, and to explore organizational aspects of MAHs related to RWD/RWE. Methods An electronic survey was conducted, and information collected directly from MAHs.
Sini M. Eskola   +5 more
wiley   +1 more source

Analysts' dividend forecasts, portfolio selection, and market risk premia [PDF]

open access: yes
The most relevant practical impediment to an application of the Markowitz portfolio selection approach is the problem of estimating return moments, in particular return expectations.
Gürtler, Marc   +2 more
core  

AI voice journaling for future language teachers: A path to well‐being through reflective practices

open access: yesBritish Educational Research Journal, EarlyView.
Abstract This study aimed to explore the perceived impact of using an AI‐powered voice journaling app in overcoming the challenges and stressors encountered by senior students enrolled in teaching practicum at an English Language Teaching Bachelor's programme.
Bora Demir, Duygu Özdemir
wiley   +1 more source

Optimal investment and asymmetric risk for a large portfolio: a large deviations approach [PDF]

open access: yes
In this study, we propose a new method based on the large deviations theory to select an optimal investment for a large portfolio such that the risk, which is defined as the probability that the portfolio return underperforms an investable benchmark, is ...
Knight, John L.   +2 more
core  

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