Results 81 to 90 of about 15,188,723 (294)

A Novel Simulation Optimization Model for the Project Portfolio Selection and Scheduling Problem Regarding the Risks of the Projects [PDF]

پژوهش در مدیریت تولید و عملیات
Purpose: Timely project completion within the predicted budget is one of the primary goals of project-oriented organizations. The inherent risks associated with projects have made achieving these goals challenging for most organizations.
Ali Namazian
doaj   +1 more source

How Does Patient Capital Enhance Agribusiness Resilience? Evidence From Chinese Listed Agribusinesses

Agribusiness, EarlyView.
ABSTRACT In emerging economies where smallholder farming dominates agricultural production, agribusinesses serve as critical intermediaries linking smallholders to broader markets, and their resilience directly affects agricultural sustainability. Short‐term‐oriented capital is reluctant to adequately finance highly uncertain and cyclical agricultural ...
Siyuan Lyu, Jianling Qi, Liling Jiang, Ronghua Jin, Yuanhao Yu, Lingjing Zhang   +5 more
wiley   +1 more source

Multi-period project portfolio selection under risk considerations and stochastic income

Journal of Industrial Engineering International, 2018
This paper deals with multi-period project portfolio selection problem. In this problem, the available budget is invested on the best portfolio of projects in each period such that the net profit is maximized.
Ali Asghar Tofighian, Hamid Moezzi, Morteza Khakzar Barfuei, Mahmood Shafiee   +3 more
doaj   +1 more source

What Explains Racial Differences in Farm Succession Planning? Evidence From Decomposition and Counterfactual Analysis

Agribusiness, EarlyView.
ABSTRACT This paper examines racial differences in farm succession planning using survey data from Tennessee farmers. While observed differences between White and Black farmers are small, decomposition and counterfactual analyses show that structural characteristics, particularly farm size, would predict higher succession planning among White farmers ...
Abdelaziz Lawani, Anna‐Liisa Ihuhwa, Armine Poghosyan   +2 more
wiley   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

Angewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma, Komal Sharma, Anku Sharma, Kamya Rao, Rahul Jain, Brett VanVeller   +5 more
wiley   +2 more sources

Modular design and supervisory control for enhanced economic resilience in continuous pharmaceutical manufacturing

AIChE Journal, EarlyView.
Abstract Conventional continuous plants use fixed‐capacity equipment, resulting in high capital risk and suboptimal performance under fluctuating demands. To address these, this study proposes an integrated framework for modular process design and supervisory control capable of adapting to demand uncertainty for long‐term economic viability.
T. Asrav, M. Alvarado‐Morales, G. Sin
wiley   +1 more source

Different Risk Measures: Different Portfolio Compositions? [PDF]

Traditionally, the measure of risk used in portfolio optimisation models is the variance. However, alternative measures of risk have many theoretical and practical advantages and it is peculiar therefore that they are not used more frequently.
Peter Byrne, Stephen Lee
core  

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source

A Scalable and Resource‐Efficient Pipelined p‐Computer for Probabilistic Ising Machines

Advanced Intelligent Systems, EarlyView.
(a) Block diagram of the portfolio optimization problem: given M assets, the goal is to determine the optimal weights w that maximize the expected return (based on the mean historical assets return u), while minimizing the risk, quantified by the assets covariance matrix S.
Deborah Volpe, Eleonora Raimondo, Andrea Grimaldi, Pedram Khalili Amiri, Stefano Chiappini, Anna Giordano, Mario Carpentieri, Hyunsoo Yang, Massimo Chiappini, Giovanni Finocchio   +9 more
wiley   +1 more source

Seeds of change: The impact of Ethiopia's direct seed marketing approach on smallholders' seed purchases and productivity

American Journal of Agricultural Economics, EarlyView.
Abstract While multiple factors explain low adoption rates of improved varieties by small‐scale farmers in sub‐Saharan Africa, a key supply‐side constraint is the limited availability of seed embodying new traits in the volume, quality, price, and timeliness required by farmers. This constraint is partly attributable to classical failures in the market
Dawit Mekonnen, Gashaw T. Abate, Seid Yimam, Rui Benfica, David J. Spielman, Frank Place   +5 more
wiley   +1 more source