Results 111 to 120 of about 1,601,504 (303)
Proyectos de Innovación: Formulación desde el Enfoque de Procesos
Journal of Technology Management & Innovation, 2008 An original proposal for the formulation of innovation projects is presented based on a process approach. The method consists on identifying the key components from the innovative idea and the corresponding processes.
Luis Felipe Miranda +1 more
doaj
Independent Animation: Exploring the Fine Line between Inspiration and Imitation [PDF]
, 2013 I came into VCU hoping to eventually go into independent animation. The UROP opportunity popped up and it sounded great and I thought, “Hey, this is something that I’ve been wanting to do.” I read the book The Evolution of Calpurnia Tate (which is a ...
Rifareal, Rebekah
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Pathos, 2013 The authors present in detail the proposal of a quality improvement project for cancer pain therapies.The project should be implemented through diagnostic and therapeutic pathways and the setting up of a community of oncologists and cancer pain experts.
Salvatore Palazzo, MD +3 more
doaj
Non-functional requirements: size measurement and testing with COSMIC-FFP [PDF]
, 2007 The non-functional requirements (NFRs) of software systems are well known to add a degree of uncertainty to process of estimating the cost of any project.
Abran, A. +3 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The design of a common lunar lander [PDF]
The Austin Cynthesis Corporation was formed to respond to a Request for Proposal for the design of a Common Lunar Lander (CLL) capable of carrying lightweight (less than 500 kg), unspecified payload to the moon. This Final Design Report Document includes
Driggers, Dan +7 more
core +1 more source
A Framework proposal for monitoring and evaluating training in ERP implementation project [PDF]
, 2003 During the last years some researchers have studied the topic of critical success factors in ERP implementations, out of which 'training' is cited as one of the most ones.
Casanovas Garcia, Josep +2 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source