Results 121 to 130 of about 1,601,504 (303)
A Suggestion for Extension of the NASA RANGER Project in Support of Manned Space Flight [PDF]
Proposal for utilizing Ranger project in support of Surveyor and Apollo ...
Moore, R. C.
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Actividad agrícola y Medio Ambiente. Propuestas de sostenibilidad en la Cuenca del Guadiamar
Anales de Geografía de la Universidad Complutense, 2004 The present paper describes ohe main results of a research project, related to the Guadiamar river disaster after a waste retention wall of a mine in Aznalcúllar broke.
MA José Prados Velasco
doaj
Letter to colleagues regarding UNDP actions in China [PDF]
Letter from Bob Seidman containing an abbreviated proposal written by himself and Ann Seidman for a United Nations Development Programme (UNDP) and Chinese Committee on International Cooperation, Exchanges, and Trade (CICET) project on bill legislation ...
Seidman, Ann, Seidman, Robert B.
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Audit, Control and Monitoring Design Patterns (ACMDP) for Autonomous Robust Systems (ARS)
International Journal of Advanced Robotic Systems, 2008 This paper proposes the Audit, Control and Monitoring Design Patterns (ACMDP) for building Autonomous and Robust Systems (ARS) such as Mobile Robot Systems (MRS).
C. Trad, A. Trad
doaj
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source