Results 51 to 60 of about 1,601,504 (303)
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
How to write a research proposal?
Writing the proposal of a research work in the present era is a challenging task due to the constantly evolving trends in the qualitative research design and the need to incorporate medical advances into the methodology.
K Sudheesh +2 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Early Cenozoic tropical climate: report from the Tanzania Onshore Paleogene Integrated Coring (TOPIC) workshop [PDF]
We are currently developing a proposal for a new International Continental Scientific Drilling Program (ICDP) project to recover a stratigraphic and paleoclimatic record from the full succession of Eocene hemipelagic sediments that are now exposed on ...
P. N. Pearson, W. Hudson
doaj +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The establishment of a young farmer in the rural economy is a key stage in the process of farm succession in the rural development environment. In this matter, Pillar II of the Common Agricultural Policy (CAP) has a distinct approach related to financing
Aurelia Ioana Chereji +6 more
doaj +1 more source
DISEÑO DE UNA PROPUESTA STEAM PARA CREAR UN ROSETÓN. ANÁLISIS EN UN CONTEXTO DE INCLUSIÓN
This work presents the design of an interdisciplinary proposal for the creation of a rosacea. The objective is to put into practice the contents of the curriculum of the Final Years of Elementary School in mathematics, connecting them with ...
Teresa Fernández Blanco +2 more
doaj +1 more source
Experimenting with the design of policies on sustainable resource management : A proposal for Cirad's involvement in a transversal socio-economics component of DMP in West Africa [PDF]
In our proposal, public policy is approached as a social mediation process, where actors and sectors confront their representations, objectives, and constraints.
Leclerc, Grégoire
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source

