Results 161 to 170 of about 520,390 (301)

Resource-constrained project scheduling for timely project completion with stochastic activity durations. [PDF]

open access: yes
We investigate resource-constrained project scheduling with stochastic activity durations. Various objective functions related to timely project completion are examined, as well as the correlation between these objectives. We develop a GRASP-heuristic to
Ballestin, F., Leus, Roel
core  

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Simulation-based framework for stochastic multi-mode resource-constrained project scheduling. [PDF]

open access: yesMethodsX
Rahimifard A   +3 more
europepmc   +1 more source

The use of buffers in project management: the trade-off between stability and makespan. [PDF]

open access: yes
During execution, projects may be subject to considerable uncertainty, which may lead to numerous schedule disruptions. Recent research efforts have focused on the generation of robust project baseline schedules that are protected against possible ...
Demeulemeester, Erik   +3 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Fixed start method for repetitive project scheduling with simulated annealing. [PDF]

open access: yesHeliyon
Moreno F   +4 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy