Results 181 to 190 of about 1,287,365 (218)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

dsLassoCov: a federated Lasso approach incorporating covariate control. [PDF]

Sci Rep
Cao H, Anguita-Ruiz A, Warembourg C, Escribà-Montagut X, Vrijheid M, Gonzalez JR, Cadman T, Setó-Llorens A, Schneider-Lindner V, Durstewitz D, Basagaña X, Schwarz E.   +11 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Integrated Genomic Analysis Uncovers the Evolutionary Landscape and Global Dissemination of Senecavirus A. [PDF]

Vet Sci
Wang W, Zhang S, Zhao Q, Jiang L, Zhu Z, Wen W, Li X.   +6 more
europepmc   +1 more source

The clinicoradiological and pathological-molecular characteristics associated with spread through air spaces in stage IA invasive lung adenocarcinoma. [PDF]

Insights Imaging
Xu F, Li X, Zhao WH, Huo JW, Luo TY, Li Q.   +5 more
europepmc   +1 more source

Co-Production Experiences in Practice From Funding to Implementation: Co-Production Experiences of Academics and Consumers in Real-World Practice. [PDF]

Health Expect
Olenski SK, Chander AR, Chambers G, Arnott L, Loxton D, Peate M, Teede H.   +6 more
europepmc   +1 more source

The Fragmented Nature of Biosensor Development: Challenges and Paths to Mitigation. [PDF]

Biosensors (Basel)
Zimran G, Mosquna A.
europepmc   +1 more source