Results 181 to 190 of about 1,363,756 (217)

AI-based multimodal fusion for preoperative prediction of breast microcalcifications: combining mammography and tomosynthesis. [PDF]

BMC Med Imaging
Wei J, Li J, Pan R, Cao M, Ma C, Xie Z, Ma Y, Gao Z.   +7 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

<i>In vivo</i> selection of anti-glioblastoma DNA aptamer-drug conjugates in an orthotopic patient-derived xenograft model. [PDF]

NAR Cancer
Doherty CD, Jain S, Ott LL, Bakken KK, Wilbanks BA, Burgenske DM, Pearson KS, Griffith JI, Tian Z, Meridew JA, Yerneni SS, Elmquist WF, Sarkaria JN, Maher Iii LJ.   +13 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Development and validation of an interpretable machine learning model integrating baseline multimodal CT perfusion and clinical data for predicting 9-month functional outcomes in acute ischemic stroke. [PDF]

Front Neurol
Zhang G, Zhang Y, Chen X, Han B, Li X, Wang Y, Jiang B.   +6 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

A Functional SNP in the Promoter Region of Ovine IDO2 Associated With Melatonin Levels via Affecting Transcription Activity by CLOCK. [PDF]

Anim Genet
Jiang X, Chi S, Wang X, Chen M, Tie Z, Yang H, Wang C, Liu G.   +7 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

How to Design and Implement a Structured Curriculum in Health Professions Education: A Nine-Step Framework Building on Kern's Approach. [PDF]

Clin Teach
Escourrou É, Oustric S.
europepmc   +1 more source

Correction: Long non-coding RNAs in glial cells: key drivers of neuroinflammation in cognitive disorders. [PDF]

Front Aging Neurosci
Malatino C, Raffaele I, Quartarone A, Raciti G, Anchesi I, Iraci N, De Cola MC.   +6 more
europepmc   +1 more source