Results 111 to 120 of about 8,460,513 (384)

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

A Naive Bayes Source Classifier for X-ray Sources

open access: yes, 2011
The Chandra Carina Complex Project (CCCP) provides a sensitive X-ray survey of a nearby starburst region over >1 square degree in extent. Thousands of faint X-ray sources are found, many concentrated into rich young stellar clusters. However, significant
Allen   +23 more
core   +1 more source

SQUARE Project Introduction and Overview

open access: yes, 2022
Presentation of the SQUARE project during the SQUARE Industry Workshop on 9.3. 2022 in Haar, Munich.
openaire   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

The application of hydrometeorological data obtained by remote sensing techniques for multipurpose reservoir operations [PDF]

open access: yes
Watershed snowpack and streamflow data obtained and transmitted by (ERTS) satellite were used in the operational and water management decisions in the Salt River Project.
Kirdar, K.   +2 more
core   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Projective normality of canonical symmetric squares

open access: yes, 2022
Recall that a smooth complex projective curve has a very ample canonical bundle when it is non-hyperelliptic, and according to a theorem of M. Noether the resulting embedding is projectively normal. A theorem of Petri further asserts that the homogeneous ideal is generated by quadrics if the curve is neither trigonal nor a smooth plane quintic. In this
openaire   +2 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Evaluation of the Effect of Project Management Techniques on Road Construction Projects in Nigeria [PDF]

open access: yesEuropean Project Management Journal, 2017
Project management is an innovative management practice that tends to achieve stated or specified objectives within specific time and budget limits through optimum use of resources. The aim of the study was to investigate the effect of project management
Onifade Morakinyo Kehinde   +2 more
doaj  

An Artificial neural networks (ANN) model for evaluating construction project performance based on coordination factors

open access: yes, 2018
Construction projects are delivered in a multidisciplinary environment, which need continues coordination. The aim of this paper is to develop an ANN model to evaluate the influence of coordination factors on construction projects performance.
W. Alaloul   +4 more
semanticscholar   +1 more source

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