Results 161 to 170 of about 245,147 (256)

Treatment of asymptomatic tuberculosis: Protocol for a systematic review of treatment strategies, regimens, and clinical outcomes. [PDF]

PLoS One
Li Y, Saad A, Feng Z, Ge S, Song L, Ren Y, Miao Y, Li T, Zhao T, Huang W, Wu J, Sun F, Wei X, Zhang W.   +13 more
europepmc   +1 more source

Nano‐Backpack Engineered Probiotics with Reactive Oxygen Species–Responsive Tungsten Release for Synergistic Therapy of Inflammatory Bowel Disease

Advanced Science, EarlyView.
An integrated probiotic system is engineered to execute a programmed therapeutic cascade against inflammatory bowel disease. Upon pathological signals, the system sequentially performs ROS scavenging, tungsten release, and selective pathogen suppression, thereby breaking the oxidative stress–dysbiosis cycle to remodel gut microbiota and reinforce ...
Yang Yang, Liucan Wang, Guoqing Chen, Yuanling Zhang, Jiarui Shi, Wenzhe Fan, Min Yu, Jixi Zhang, Hua Yang   +8 more
wiley   +1 more source

International Case Studies to Identify Success Factors and Contextual Conditions in the Digital Transformation of Health Care Systems and Derive Lessons for Germany: Study Protocol for a Mixed Methods Study. [PDF]

JMIR Res Protoc
Kraft L, Brecher AL, Sgraja S, Busse R, Amelung VE.   +4 more
europepmc   +1 more source

Calcineurin‐Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata

Advanced Science, EarlyView.
Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su, Yi Li, Meng Xiao, Dan Guo, David S. Perlin, Erika Shor, Yingchun Xu, Yingxing Li   +7 more
wiley   +1 more source

Success criteria comparison of eight implemented projects to improve the planning, design, and construction of floodplain wetlands. [PDF]

PLOS Water
Hawley RJ, Nietch C, Knight D, Acosta S, Cooper K, Korth N, Raetz A, McManus J, McClatchy R, Hahn J, Lubbers H, Lair L, Winston RJ.   +12 more
europepmc   +1 more source

EpCAM+ Extracellular Vesicle PD‐L1 Dynamics as a Predictive Biomarker of Immune Checkpoint Blockade Response

Advanced Science, EarlyView.
A highly sensitive SERS‐based platform measures PD‐L1 expression on EpCAM+ circulating EVs from cancer patients undergoing immunotherapy. Monitoring dynamic changes after treatment reveals that reduced EpCAM+ EV PD‐L1 levels associate with improved long‐term clinical outcomes, establishing a non‐invasive approach for tracking immune checkpoint ...
Byeonggeol Mun, Jinyoung Kim, Chang Gon Kim, Seokhyeong Go, Mina Han, Yujin Ouck, Soojin Jang, Seong Uk Son, Gamin Kim, Wonrak Son, Eunjung Kim, Min Hee Hong, Ja Hyun Yeo, Eun‐Kyung Lim, Hye Ryun Kim, Seungjoo Haam   +15 more
wiley   +1 more source

TheraCal LC versus Mineral Trioxide Aggregate for full pulpotomy in cariously exposed mature permanent molars with symptomatic irreversible pulpitis: a randomized clinical trial. [PDF]

Biomater Investig Dent
Ravi V, Namdev R, Singhal R, Sharma M, Dayma C, Rani A.   +5 more
europepmc   +1 more source

A Generative Neuro‐Symbolic AI for Protein Sequence Design

Advanced Science, EarlyView.
We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne, Delphine Dessaux, Samuel Buchet, Lucie Barthe, Liza Ammar‐Khodja, Bessam Azizi, Valentin Durante, Gianluca Cioci, Simon de Givry, Alain Roussel, Luis F. Garcia‐Alles, Thomas Schiex, Sophie Barbe   +12 more
wiley   +1 more source

High-fidelity simulation in airway management training: results from the AIR-MASTER-SIM randomised study. [PDF]

Front Med (Lausanne)
Puerma-Jiménez J, Pérez-Villares JM, Domínguez-Guzmán P, Gómez-Moreno G, Parrilla-Ruiz FM, Carrasco-Cáliz A, Fernández-Florido P, Cárdenas-Cruz A.   +7 more
europepmc   +1 more source

Efficient Hot Carrier Management in Lead Halide Perovskite Micro‐Disks Revealed by Super‐Diffusive Migration

Advanced Science, EarlyView.
Hot‐carrier transport in metal halide perovskites is investigated using spatiotemporally‐resolved photoluminescence microscopy. Mesa‐shaped MAPbBr3 microdisks exhibit anomalous super‐diffusive carrier propagation on nanosecond timescales, driven by hot‐carrier stabilization and strong carrier–phonon coupling.
Nithin Pathoor, Shun Omagari, Martin Vacha   +2 more
wiley   +1 more source