Results 51 to 60 of about 1,568,481 (304)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

The influence of factors on project management: a qualitative approach [PDF]

open access: yesProduction
Paper aims This study describes a qualitative analysis methodology, proposing measurement of the degree of influence of factors acting in project management.
José Francisco Tebaldi de Castro   +4 more
doaj   +2 more sources

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye   +11 more
wiley   +1 more source

Exploring Success Criteria from the Developers' Perspective in Malaysia

open access: yesInternational Journal of Engineering Business Management, 2012
There are many different sets of project success criteria, but none of them will be suitable for all of the different stakeholders involved in the construction industry.
S.H. Wai   +2 more
doaj   +1 more source

Healthy ageing in Europe: prioritizing interventions to improve health literacy [PDF]

open access: yes, 2016
Background: Health literacy (HL) is low for 40-50% of the population in developed nations, and is strongly linked to many undesirable health outcomes. Older adults are particularly at risk.
Alexandra Makai   +8 more
core   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang   +22 more
wiley   +1 more source

Criteria For Selection And Gate Reviews Of Technology Innovation Projects

open access: yesSouth African Journal of Industrial Engineering, 2014
This paper describes appropriate project selection criteria and gate review-point criteria for government agencies that fund technology innovation projects in South Africa.
Steyn, Herman, Binneman, Brigitte
doaj   +1 more source

Undergraduate interior design program admissions: What is the best predictor of future “success?” [PDF]

open access: yes, 2009
The purpose of this paper is to present initial findings of a quasi-experimental study that analyzes what selection criteria provide the best measures of predicting future “success” in an undergraduate interior design program.
Brunner, Lori A.
core   +1 more source

Innovative Tourism Clusters: Myth or Reality? Empirical Evidence from Benidorm [PDF]

open access: yes, 2014
Paper submitted to TCVT3 Bozen/Bolzano, 10-12 April 2014, International workshop on Tourists as Consumers, Visitors, TravellersThis paper analyses the applicability of the cluster concept to tourist destinations, taking Benidorm as the reference for ...
Perles Ribes, José Francisco   +2 more
core   +1 more source

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