Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Nipple Reconstruction Using FixNip NRI: A Novel Nipple Reconstruction Implant (First-in-human Trial). [PDF]
Konfino T +4 more
europepmc +1 more source
Projection-Based Coordinated Scheduling of Distribution–Microgrid Systems Considering Frequency Security Constraints [PDF]
Xiaoxu Song +5 more
openalex +1 more source
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
Fringe-Based Structured-Light 3D Reconstruction: Principles, Projection Technologies, and Deep Learning Integration. [PDF]
Zhang Z +8 more
europepmc +1 more source
Probabilistic 21st and 22nd century sea‐level projections at a global network of tide‐gauge sites
Robert E. Kopp +7 more
openalex +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Dual-Head Pix2Pix Network for Material Decomposition of Conventional CT Projections with Photon-Counting Guidance. [PDF]
Liu Y +9 more
europepmc +1 more source
Event-camera enhanced RatSLAM: A Multi-View Projection-Based Loop Closure Detection Method
H.-Q. Wang +4 more
openalex +1 more source

