Results 171 to 180 of about 29,170 (215)
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
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2021
This chapter emphasizes a major theme in Dublin's eighteenth-century history: the battle to control and develop urban space, to mitigate the effects of growth, and to adapt new concepts of urban form. The chapter begins with narrating the baroque urban planning led by the first Duke of Ormond that had profound consequences for the Irish capital.
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This chapter emphasizes a major theme in Dublin's eighteenth-century history: the battle to control and develop urban space, to mitigate the effects of growth, and to adapt new concepts of urban form. The chapter begins with narrating the baroque urban planning led by the first Duke of Ormond that had profound consequences for the Irish capital.
openaire +2 more sources
IEEE Micro, 1987
TRON designates a family of architectures, operating system kernels, and VLSI CPU chips. It is an open specification, intended to foster the development of compatible products by many vendors.
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TRON designates a family of architectures, operating system kernels, and VLSI CPU chips. It is an open specification, intended to foster the development of compatible products by many vendors.
openaire +3 more sources
Theoretical Computer Science, 2019
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Vittorio Bilò +2 more
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zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Vittorio Bilò +2 more
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Project Management Journal, 2006
The fit between project managers' personality and management style and the types of projects they manage is crucial for projects' success. This exploratory interdisciplinary study focuses on the relationships among three aspects: projects' types (profiles), project managers' personality, and projects' success.
Dov Dvir, Arik Sadeh, Ayala Malach-Pines
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The fit between project managers' personality and management style and the types of projects they manage is crucial for projects' success. This exploratory interdisciplinary study focuses on the relationships among three aspects: projects' types (profiles), project managers' personality, and projects' success.
Dov Dvir, Arik Sadeh, Ayala Malach-Pines
openaire +1 more source
1988
This short paper briefly describes the ALGRES project, an advanced relational programming environment for the specification and rapid prototyping of data-intensive applications. ALGRES is a vehicle for the integration of two research areas: the extension of the relational model to deal with complex objects and operations, and the integration of ...
Ceri S. +6 more
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This short paper briefly describes the ALGRES project, an advanced relational programming environment for the specification and rapid prototyping of data-intensive applications. ALGRES is a vehicle for the integration of two research areas: the extension of the relational model to deal with complex objects and operations, and the integration of ...
Ceri S. +6 more
openaire +3 more sources
2003 IEEE International Conference on Robotics and Automation (Cat. No.03CH37422), 2004
Ultrasound technologies have been widely used in gynecology and obstetrics. Modern ultrasound systems allow the reconstruction of a 3D model of the subject being scanned. Even though visual interfaces have reached very high standards, the problem of representing a 3D image on a 2D computer screen still exists.
La Torre B. +3 more
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Ultrasound technologies have been widely used in gynecology and obstetrics. Modern ultrasound systems allow the reconstruction of a 3D model of the subject being scanned. Even though visual interfaces have reached very high standards, the problem of representing a 3D image on a 2D computer screen still exists.
La Torre B. +3 more
openaire +2 more sources
Teaching Project Planning with No Project
2016 IEEE 29th International Conference on Software Engineering Education and Training (CSEET), 2016This paper describes a technique for teaching students about project estimating, planning and tracking in courses where there is no student project. The technique involves treating the course itself as the project. The technique is particularly useful in project management courses offered via distance education (for which team projects are not always ...
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