Results 131 to 140 of about 3,400,583 (308)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
, 1941 This is the 1941 edition of the College of Wooster\u27s Index. The Index is written by student editors, and it is the college’s yearbook, it includes an annual record of events at Wooster. This specific edition begins with quiz questions, and the answers
Editors, Index
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
, 1914 This is volume 33 of the College of Wooster’s Index collection. The Index is the college’s yearbook, it includes an annual record of the events at Wooster. This edition was published by the class of 1914.
Index Editors,
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Multi-wavelength structured light based on metasurfaces for 3D imaging
NanophotonicsStructured light projection provides a promising approach to achieving fast and non-contact three-dimensional (3D) imaging. The resolution is a crucial index that represents security and accuracy in applications such as face recognition and robot vision.
Lyu Baiying +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
, 1944 This is the 1944 edition of the Index. The Index is written by student editors, and it is the college’s yearbook. It includes an annual record of events at Wooster.
Index Editors,
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
, 2009 This is the College of Wooster Index from 2009. The sections of the Index include Student Life, Politics, Sports, Seniors, and Organizations. The Index also features information about renovations of Beall Ave.
Editors, Index
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source