Results 61 to 70 of about 3,400,583 (308)
Frontiers in Earth ScienceAccurately classifying swell potential grades of clayey soils remains a significant challenge in geotechnical engineering, primarily due to the complex interplay of multiple factors that govern swelling-shrinkage behavior.
Kangming Lou +14 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
StatVis: A visual analytics framework for statistical cluster validation in high dimensions
ArrayHigh-dimensional datasets are common across scientific and industrial domains, yet interpreting their clustering outcomes remains a complex challenge due to projection distortions and metric ambiguities.
Donia Y. Badawood
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
On Projective Umbilics: a Geometric Invariant and an Index [PDF]
Journal of Singularities, 2018 13 pages, 7 ...
openaire +4 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Projection Pursuit Dynamic Cluster Model and Its Application in Groundwater Classification
工程科学与技术, 2006 :A projection pursuit dynamic cluster (PPDC) model is proposed, which combines projection pursuit principle with dynamic cluster rule. Firstly, multifactor cluster problem is converted into single-factor cluster problem according to linear projection ...
doaj
Complex & Intelligent SystemsAs a carrier of multi-industrial technology integration and the key to industrial competition, the intelligent connected vehicle (ICV) has been taken seriously around the world. However, as a fast-growing emerging industry, its development process varies
Yi Wang +3 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source