Results 81 to 90 of about 439,416 (273)
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Towards coarse-grained modelling of proteins
Condensed Matter Physics, 2007 This paper introduces a basic theoretical background to the description of conformational dynamics of proteins through a system of interacting domains.
M.Stepanova
doaj +1 more source
Computing a projection operator onto the null space of a linear imaging operator: tutorial. [PDF]
J Opt Soc Am A Opt Image Sci Vis, 2022 Kuo J +3 more
europepmc +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Output feedback maneuvering control of random Lagrange systems with actuator malfunctions
Electronic Research ArchiveIn this paper, a fault-tolerant output feedback maneuvering control scheme with prescribed performance for a class of random Euler–Lagrange systems with unmeasurable velocity and actuator faults is presented.
Cun Yang
doaj +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Finite-rank intermediate Hankel operators on the Bergman space
International Journal of Mathematics and Mathematical Sciences, 2001 Let L2=L2(D,r dr dθ/π) be the Lebesgue space on the open unit disc and let La2=L2∩ℋol(D) be the Bergman space. Let P be the orthogonal projection of L2 onto La2 and let Q be the orthogonal projection onto L¯a,02={g∈L2;g¯∈La2, g(0)=0}. Then I−P≥Q.
Takahiko Nakazi, Tomoko Osawa
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source