Results 131 to 140 of about 2,144,760 (295)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Jixie chuandong, 2010 In order to establish the straight bevel gear sketches and simulation model database,the straight bevel gear profile involute mathematical model is established,and a bevel gear tooth involute profile of the spherical projection formed into the circle ...
胡志勇, 张国兴, 刘海, 刘长增
doaj
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Profile of Canadiana.org digitization project
, 2008 Brian Bell, Canadiana.org: One of Canada's oldest and newest digitization initiatives, Partnership: the Canadian Journal of Library and Information Practice and Research 3(1), 2008.
openaire +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
A Three-Dimensional Reconstruction Method Based on Telecentric Epipolar Constraints
PhotonicsWhen calibrating a microscopic fringe projection profile system with a telecentric camera, the orthogonality of the camera causes an ambiguity in the positive and negative signs of its external parameters.
Qinsong Li +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Dissemination material and communication channels: logo, public document templates, website, social media.
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Profile of Wikipedia and Project Gutenberg
, 2008 Terry Hancock, Impossible thing #2: Comprehensive free knowledge repositories like Wikipedia and Project Gutenberg, Free Software Magazine, February 19, 2008. A profile and analysis of the Wikipedia and Project Gutenberg OA projects.
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