Results 231 to 240 of about 10,982 (282)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Fluoroscopy-Guided Motion Management in Particle Therapy: Evolution, Challenges, and AI-Enabled Opportunities. [PDF]

Tomography
Li F, Furutani KM, Beltran CJ.
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

A Sparse Bayesian Technique to Learn the Frequency-Domain Active Regressors in OFDM Wireless Systems. [PDF]

Sensors (Basel)
Crespo-Cadenas C, Madero-Ayora MJ, Becerra JA, Marqués-Valderrama E, Cruces S.   +4 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Ab Initio Binocular Formulation of Listing's Law. [PDF]

J Eye Mov Res
Turski J.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Balancing acts: lateral hypothalamic circuits coordinating feeding, anxiety, and social interactions. [PDF]

Rev Endocr Metab Disord
Korotkova T.
europepmc   +1 more source

Robust Camera-Based Eye-Tracking Method Allowing Head Movements and Its Application in User Experience Research. [PDF]

J Eye Mov Res
Zhang H, Yin L.
europepmc   +1 more source

NeMO Analytics: a compendium of transcriptomic data for the exploration of neocortical development. [PDF]

Nat Neurosci
Sonthalia S, Herb B, Adkins RS, Orvis J, Li G, Liao X, Yu Q, Blanco XM, Casella A, Liu J, Stein-O'Brien G, Caffo B, Hertzano R, Mahurkar A, Xu JC, Gillis J, Werner J, Ma S, Kim SK, Micali N, Sestan N, Rakic P, Santpere G, Ament SA, Colantuoni C.   +24 more
europepmc   +1 more source