Results 201 to 210 of about 354,550 (267)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Whole-brain efferent projections of glutamatergic neurons in the cingulate cortex of mice. [PDF]

Mol Brain
Shi F, Lei L, Qiu J, Zhu Y, Wu H, Wu X.
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Quasi-global, land-only, high-resolution and spatially averaged climate variables from downscaled CMIP6 models for climate impact research

Jahn S, Gaythorpe KAM, Dorigatti I, Winskill P, Hinsley W, Wainwright CM, Toumi R, Ferguson NM.   +7 more
europepmc   +1 more source

Global Skin Cancer Burden From 1990 to 2023 and Projection to 2050.

JAMA Dermatol
Zhou Y, Zhong W, Liu X, Zhang J.
europepmc   +1 more source

Machine learning helps to strongly reduce future warming uncertainty. [PDF]

Nat Commun
Li C, Wu J, Wang Z, Zwiers FW, Zhang X, Chen X.   +5 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Forecasting preterm birth in Kazakhstan through 2050: a cohort-component demographic modeling study. [PDF]

Glob Health Action
Issenova S, Altynbayeva G, Kussainov A, Issina G, Bishekova B, Sultanmuratova D.   +5 more
europepmc   +1 more source