Results 41 to 50 of about 53,564 (278)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Geometry of LP-Sasakian Manifolds Admitting a General Connection

open access: yesMathematics
This paper concerns certain properties of projective curvature tensor, conharmonic curvature tensor, quasi-conharmonic curvature tensor, and Ricci semi-symmetric conditions with respect to the general connection in an LP-Sasakian manifold.
Rajesh Kumar   +3 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Sobre o desenho e design

open access: yesPós: Revista do Programa de Pós-Graduação em Arquitetura e Urbanismo da FAUUSP, 2001
The discussion about the meaning of words used to name designer activity, or “ industrial design” as it was known up to the decade of the 1970’s, mainly revolved around the notion of a constructive approach.
Mauro Claro
doaj   +3 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Decomposition of the connection in affine models of gravity

open access: yesEuropean Physical Journal C: Particles and Fields
In physics geometrical connections are the mean to create models with local symmetries (gauge connections), as well as general diffeomorphisms invariance (affine connections).
Oscar Castillo-Felisola   +3 more
doaj   +1 more source

The Concept of Social Connection by Agnesa Zvonytska

open access: yesВісник Харківського національного університету імені В.Н. Каразіна. Серія: Соціологічні дослідження сучасного суспільства: методологія, теорія, методи, 2022
The article considers the problems of the sociological concept of social connection by the first Ukrainian female researcher, A. Zvonytska, and establishes connections between her and modern sociological theories. It is noted that A.
Ekateryna Bataeva
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

PDA with Independent Counters

open access: yesМоделирование и анализ информационных систем, 2015
Push-down automata with independent counters (PDACs) combine the power of PDAs and Petri Nets. They were developed in [21, 15], as a tool of recognition of languages generated by Categorial Dependency Grammars (CDGs).
Michael Dekhtyar, Boris Karlov
doaj   +1 more source

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