Results 61 to 70 of about 186,600 (323)
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Tropical Balls and Its Applications to K Nearest Neighbor over the Space of Phylogenetic Trees
Mathematics, 2021 A tropical ball is a ball defined by the tropical metric over the tropical projective torus. In this paper we show several properties of tropical balls over the tropical projective torus and also over the space of phylogenetic trees with a given set of ...
Ruriko Yoshida
doaj +1 more source
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Embedding dual nets in affine and projective spaces [PDF]
Rendiconti di Matematica e delle Sue Applicazioni, 1994 This article determines the structure of arbitrary nets (finite or infinite) whose duals may be embedded into affine or projective space. The main results are that nets whose duals may be embedded into projective space are pseudo-regulus nets and nets ...
N.L. JOHNSON, K.S. LIN
doaj
Projective and other locative PPs in Greek
Glossa, 2022 The distinction between projective and non-projective locative prepositions that has been proposed in the semantic literature (Zwarts & Winter 2000) is reflected in the syntax and morphology of Greek spatial expressions.
Athanasios Michail Ramadanidis
doaj +2 more sources
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Dynamics of real projective transformations
Applied General Topology, 2018 The dynamics of a projective transformation on a real projective space are studied in this paper. The two main aspects of these transformations that are studied here are the topological entropy and the zeta function.
Sharan Gopal, Srikanth Ravulapalli
doaj +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
On projections of metric spaces
Journal of Computational Geometry, 2011 Journal of Computational Geometry, Vol. 5 No. 1 (2014)
openaire +4 more sources