Results 121 to 130 of about 8,655,830 (348)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Epimorphisms and maximal covers in categories of compact spaces
Applied General Topology, 2013 The category C is "projective complete"if each object has a projective cover (which is then a maximal cover). This property inherits from C to an epireflective full subcategory R provided the epimorphisms in R are also epi in C. When this condition fails,
B. Banaschewski, A.W. Hager
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DENSITY CONCOMITANTS OF THE CURVATURE TENSOR Rαᵦᵧᵟ IN THE PROJECTIVE-EUCLIDEAN SPACE [PDF]
, 1976 Leon Bieszk, Danuta Stygar
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Spin Algebra and Naimark’s Extension: A Tutorial Approach with Examples
East European Journal of PhysicsIn analyzing two-electron systems, the interactions of interest often include the spin-spin operator S→1×S→2) and the spin-orbit operator L→·S→. When these operators act on entangled or indistinguishable particles, their measurement and physical ...
Sumita Datta
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Invariants on Projective Space [PDF]
Journal of the American Mathematical Society, 1994 The paper contains some new theorems and examples of constructions of invariant nonlinear differential operators on real \(n\)-spheres. The classical theory of H. Weyl is essentially and practically extended. The results concerning spheres are transferred to projective spaces.
openaire +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
NON-COMMUTATIVE COMPLEX PROJECTIVE SPACES AND THE STANDARD MODEL [PDF]
, 2003 BRIAN P. DOLAN
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source