Results 181 to 190 of about 90,958 (327)

Functionally distinct GABAergic amacrine cell types regulate spatiotemporal encoding in the mouse retina. [PDF]

Nat Neurosci
Matsumoto A, Morris J, Looger LL, Yonehara K.   +3 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Construction and Initial Psychometric Validation of the Morana Scale: A Multidimensional Projective Tool Developed Using AI-Generated Illustrations. [PDF]

J Clin Med
Koweszko T, Kukulska N, Gierus J, Silczuk A.   +3 more
europepmc   +1 more source

Pressurized fluidized-bed combustion combustion test and integration unit, PFBC/CTIU project. ANL monthly progress report, October 1977

, 1977
L. Leffler
openalex   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Cancer Prevention at Work (CPW) project: Rationale, framework and research protocol. [PDF]

PLoS One
Kostrzewa M, Sadat Seyyedsalehi M, Godono A, Collatuzzo G, Fiorini G, Moscato S, Santello A, Roth C, Wensing M, Massimino G, Cella MT, Biagioli V, Magaña M, Pinto-Vidal FA, Klöslová Z, Oravec Bérešová J, Bruno D, Giordani S, Kočtúchová Blažinová M, Vilček R, Otelea MR, Popescu FG, Crull I, Gili R, Gorra E, Fernandez-Tardon G, Rodriguez-Suarez MM, Calota V, Askegaard S, Honrado Á, Tardon A, Fabiánová E, Vencovsky D, Schneider-Kamp A, Mates D, Mellone S, Boffetta P.   +36 more
europepmc   +1 more source

Meeting the Standards of the Standardized Test: How Does Project-Based Learning Correlate to Traditional Learning in an Advanced Placement English Language and Composition Course?

, 2013
Colette Armstrong-Grodzicki
openalex   +1 more source

Materials Testing Reactor Project, Argonne National Laboratory, Design Report No. 32, MTR External Air System

, 1950
C.F. Leyse
openalex   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Comparing conventional and Bayesian workflows for clinical outcome prediction modelling with an exemplar cohort study of severe COVID-19 infection incorporating clinical biomarker test results. [PDF]

BMC Med Inform Decis Mak
Sullivan B, Barker E, MacGregor L, Gorman L, Williams P, Bhamber R, Thomas M, Gurney S, Hyams C, Whiteway A, Cooper JA, McWilliams C, Turner K, Dowsey AW, Albur M.   +14 more
europepmc   +1 more source