Results 201 to 210 of about 16,805,041 (383)

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

FEBS Open Bio, EarlyView.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo, Klaudia Jaczynska, Christian Rosenmund   +2 more
wiley   +1 more source

Robust estimation of the intrinsic dimension of data sets with quantum cognition machine learning. [PDF]

Sci Rep
Candelori L, Abanov AG, Berger J, Hogan CJ, Kirakosyan V, Musaelian K, Samson R, Smith JET, Villani D, Wells MT, Xu M.   +10 more
europepmc   +1 more source

Comparative activity of dimethyl fumarate derivative IDMF in three models relevant to multiple sclerosis and psoriasis

FEBS Open Bio, EarlyView.
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He, Guiyi Gong, Geovani Quijas, Simon Ming‐Yuen Lee, Ratan K. Chaudhuri, Krzysztof Bojanowski   +5 more
wiley   +1 more source

An operational distinction between quantum entanglement and classical non-separability. [PDF]

Philos Trans A Math Phys Eng Sci
Korolkova N, Sánchez-Soto L, Leuchs G.
europepmc   +1 more source

The Relationship Between Trait and State Anxiety and a Projective Personality Test.

, 1971
Harold Coco
openalex   +2 more sources

Third Report of the Normandy Reservoir Salvage Project: 1973 Testing Program, Lithic Resource Survey, Lithic Annealing Project, and Report on Plant and Faunal Remains from the Banks III Site. C. R. Mc‐Collough and Charles H. Faulkner [PDF]

, 1978
Carl Kuttruff
openalex   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Gender Determination Through Mandibular Features on Orthopantomograms: A Preliminary Study. [PDF]

Cureus
Arthanari A, Ravindran V, Ramalingam K, Prathap L, Raj S.   +4 more
europepmc   +1 more source

Project Rio Blanco: comparative postdetonation hydrologic testing

, 1974
C.F. Knutson
openalex   +1 more source

A potential tumor suppressor role of PLK2 in glioblastoma

FEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia, Peirui Wang, Hua Xiao, Qishan Ran, Yan Li, Shengtao Yao   +5 more
wiley   +1 more source