Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
The process of latency in current clinical: study through projective methods (Rorschach and T.A.T.).
Our research, based on the contribution of projective methods, by Rorschach Test and the Thematic Apperception Test, should bring us data rather disturbing in so-called normal latencies, particularly in the cohesion of self, organizing drives, the ...
Tiziana Sola +3 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Representation of Motherhood and Age Characteristics of Infants in Girls in their Late Teens [PDF]
We describe and analyze data on changes in the representations of motherhood and age characteristics of infants under the influence of pregnancy and motherhood experiences with girls in their late teens (we studied three groups: having no children ...
Krys’ko A.A., , Lantsburg M.E.,
doaj
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Experimental proof of quantum Zeno-assisted noise sensing
In the ideal quantum Zeno (QZ) effect, repeated quantum projective measurements can freeze the coherent dynamics of a quantum system. However, in the weak QZ regime, measurement back-actions can allow the sensing of semi-classical field fluctuations.
Hoang-Van Do +8 more
doaj +1 more source
Semisimple Quantum Cohomology and Blow-ups
Using results of Gathmann, we prove the following theorem: If a smooth projective variety X has generically semisimple (p,p)-quantum cohomology, then the same is true for the blow-up of X at any number of points.
Bayer, Arend
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Common and professional psychological help: conceptual framework and issues
The article is devoted to the analysis of some phenomena of professional and non- professional (“common”) help. Approaches to the study of assistance forms and strategies that are linked with empathy, consolation and support are viewed.
Sheryagina E.V.
doaj +1 more source

