Results 71 to 80 of about 17,189,290 (335)
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Contemporary Clinical Dentistry, 2015 Introduction: Dental treatment is usually a poignant phenomenon for children. Projective scales are preferred over psychometric scales to recognize it, and to obtain the self-report from children.
Nishidha Tiwari +5 more
doaj +1 more source
FEBS Letters, EarlyView.PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley +1 more source
The process of latency in current clinical: study through projective methods (Rorschach and T.A.T.).
Mediterranean Journal of Clinical Psychology, 2013 Our research, based on the contribution of projective methods, by Rorschach Test and the Thematic Apperception Test, should bring us data rather disturbing in so-called normal latencies, particularly in the cohesion of self, organizing drives, the ...
Tiziana Sola +3 more
doaj +1 more source
Hermann Rorschach: From klecksography to psychiatry
Dementia & Neuropsychologia, 2020 Hermann Rorschach was a Swiss psychiatrist and psychoanalyst, best known for developing a projective test known as the Rorschach inkblot test, a test designed to reflect unconscious parts of the personality that project into the visual stimuli generated ...
Ricardo Vieira Teles Filho
doaj +1 more source
On K-Stability of Reductive Varieties
, 2003 G. Tian and S.K. Donaldson formulated a conjecture relating GIT stability of a polarized algebraic variety to the existence of a Kahler metric of constant scalar curvature.
Alexeev, Valery, Katzarkov, Ludmil
core +3 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Representation of Motherhood and Age Characteristics of Infants in Girls in their Late Teens [PDF]
Психологическая наука и образование (2007. Online), 2014 We describe and analyze data on changes in the representations of motherhood and age characteristics of infants under the influence of pregnancy and motherhood experiences with girls in their late teens (we studied three groups: having no children ...
Krys’ko A.A., , Lantsburg M.E.,
doaj
Experimental Test of Quantum Jarzynski Equality with a Trapped Ion System
, 2014 The past two decades witnessed important developments in the field of non-equilibrium statistical mechanics. Among these developments, the Jarzynski equality, being a milestone following the landmark work of Clausius and Kelvin, stands out. The Jarzynski
An, Shuoming +8 more
core +1 more source