Results 81 to 90 of about 17,189,290 (335)
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Experimental proof of quantum Zeno-assisted noise sensing
New Journal of Physics, 2019 In the ideal quantum Zeno (QZ) effect, repeated quantum projective measurements can freeze the coherent dynamics of a quantum system. However, in the weak QZ regime, measurement back-actions can allow the sensing of semi-classical field fluctuations.
Hoang-Van Do +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Measuring Responses to Commercials: A Projective-Elicitation Approach [PDF]
, 2006 Photoelicitation and projective assessment are research methods derived from visual sociology and psychoanalysis respectively. This study combined the methods by having respondents view a commercial, and then showing them one of two versions of a ...
Soley, Lawrence
core +1 more source
Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
Common and professional psychological help: conceptual framework and issues
Консультативная психология и психотерапия, 2016 The article is devoted to the analysis of some phenomena of professional and non- professional (“common”) help. Approaches to the study of assistance forms and strategies that are linked with empathy, consolation and support are viewed.
Sheryagina E.V.
doaj +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Evaluate attitudes schools' Principals towards some educational concepts [PDF]
Journal of Islamic Studies, 1981 Since 1972 Faculty of Education began to organise training programs for the directors of primary schools in Saudi Arabia. This study aims to evaluate these programms to verify whether it could achieve its goal or not.
Mahmoud Mohamed El-Ziadi
doaj
Evaluating Public Policy Formation and Support Mechanisms for Technological Innovation [PDF]
Policy evaluation is a complex task. Most approaches now adopt a mixed method approach combining both quantitative and qualitative techniques. A shortcoming of the standard approaches is that they fail to measure or investigate deeper perceptions of the ...
Bond, Derek, Ramsey, Elaine
core +1 more source
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source