Results 81 to 90 of about 88,456 (340)

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Representation of Motherhood and Age Characteristics of Infants in Girls in their Late Teens [PDF]

open access: yesПсихологическая наука и образование (2007. Online), 2014
We describe and analyze data on changes in the representations of motherhood and age characteristics of infants under the influence of pregnancy and motherhood experiences with girls in their late teens (we studied three groups: having no children ...
Krys’ko A.A., , Lantsburg M.E.,
doaj  

Entanglement in Mesoscopic Structures: Role of Projection

open access: yes, 2003
We present a theoretical analysis of the appearance of entanglement in non-interacting mesoscopic structures. Our setup involves two oppositely polarized sources injecting electrons of opposite spin into the two incoming leads.
A. Aspect   +24 more
core   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Experimental proof of quantum Zeno-assisted noise sensing

open access: yesNew Journal of Physics, 2019
In the ideal quantum Zeno (QZ) effect, repeated quantum projective measurements can freeze the coherent dynamics of a quantum system. However, in the weak QZ regime, measurement back-actions can allow the sensing of semi-classical field fluctuations.
Hoang-Van Do   +8 more
doaj   +1 more source

Rational Complexity-One T-Varieties are Well-Poised

open access: yes, 2017
Given an affine rational complexity-one $T$-variety $X$, we construct an explicit embedding of $X$ in affine space $\mathbb{A}^n$. We show that this embedding is well-poised, that is, every initial ideal of $I_X$ is a prime ideal, and determine the ...
Ilten, Nathan, Manon, Christopher
core   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

Evaluating Public Policy Formation and Support Mechanisms for Technological Innovation [PDF]

open access: yes
Policy evaluation is a complex task. Most approaches now adopt a mixed method approach combining both quantitative and qualitative techniques. A shortcoming of the standard approaches is that they fail to measure or investigate deeper perceptions of the ...
Bond, Derek, Ramsey, Elaine
core   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

Common and professional psychological help: conceptual framework and issues

open access: yesКонсультативная психология и психотерапия, 2016
The article is devoted to the analysis of some phenomena of professional and non- professional (“common”) help. Approaches to the study of assistance forms and strategies that are linked with empathy, consolation and support are viewed.
Sheryagina E.V.
doaj   +1 more source

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