Results 81 to 90 of about 16,805,041 (383)
Molecular Oncology, EarlyView.In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen +13 more
wiley +1 more source
Common and professional psychological help: conceptual framework and issues
Консультативная психология и психотерапия, 2016 The article is devoted to the analysis of some phenomena of professional and non- professional (“common”) help. Approaches to the study of assistance forms and strategies that are linked with empathy, consolation and support are viewed.
Sheryagina E.V.
doaj +1 more source
Introducing Automated Regression Testing in Open Source Projects [PDF]
arXiv, 2010 To learn how to introduce automated regression testing to existing medium scale Open Source projects, a long-term field experiment was performed with the Open Source project FreeCol. Results indicate that (1) introducing testing is both beneficial for the project and feasible for an outside innovator, (2) testing can enhance communication between ...
arxiv
Molecular Oncology, EarlyView.This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina +17 more
wiley +1 more source
Evaluate attitudes schools' Principals towards some educational concepts [PDF]
Journal of Islamic Studies, 1981 Since 1972 Faculty of Education began to organise training programs for the directors of primary schools in Saudi Arabia. This study aims to evaluate these programms to verify whether it could achieve its goal or not.
Mahmoud Mohamed El-Ziadi
doaj
Molecular Oncology, EarlyView.We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić +31 more
wiley +1 more source
Molecular Oncology, EarlyView.Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale +9 more
wiley +1 more source
Molecular Oncology, EarlyView.The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu +3 more
wiley +1 more source
DDTS: A Practical System Testing Framework for Scientific Software [PDF]
arXiv, 2014 Many scientific-software projects test their codes inadequately, or not at all. Despite its well-known benefits, adopting routine testing is often not easy. Development teams may have doubts about establishing effective test procedures, writing test software, or handling the ever-growing complexity of test cases.
arxiv