Results 101 to 110 of about 293 (264)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Restricted Non-Projectivity: Coverage vs. Efficiency

open access: yesComputational Linguistics, 2021
Carlos Gómez-Rodríguez
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Free Banach lattices under convexity conditions. [PDF]

open access: yesRev R Acad Cienc Exactas Fis Nat A Mat, 2022
Jardón-Sánchez H   +4 more
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

DISCOURSE WORLD AS PROJECTIVE MACROREALITY IN BRITISH ADVERTISING: COGNITIVE-SEMANTIC ANALYSIS

open access: yesВестник Кемеровского государственного университета, 2015
Advertising discourse is analyzed from projectivity perspective: with regard to the construction of the global discourse meaning known as “discourse world” as mental macroreality exposed to marketing laws.
S. L. Kushneruk
doaj  

Heritability of types of a pregeometry relative to a family of relational structures

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
A series of geometrical and topological properties induced by structures, including degeneration, modularity, local modularity, projectivity, local finiteness, etc., play an important role in clarifying structural relationships and in classifying basic ...
S.B. Malyshev, S.V. Sudoplatov
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

SCIENTIFIC, ARTISTIC AND SOCIAL ASPECTS OF THE CONCEPTUALIZATION OF SPACE IN THE ENLIGHTENMENT

open access: yesRussian Studies in Culture and Society
The article is devoted to the study of the conceptualization of space in the Enlightenment. The author examines the scientific approach to space that developed in the New Age, the artistic understanding of space and the practices of vision that manifest ...
Marina A. Vasilyeva
doaj   +1 more source

Scalable NMF via linearly optimized data compression. [PDF]

open access: yesProc SPIE Int Soc Opt Eng, 2023
Ha SM, Bani A, Sotiras A.
europepmc   +1 more source

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