Results 161 to 170 of about 9,608,719 (352)

The archaeological direction in Japanese studies in Russia: Development, peculiarities, personal experience

open access: yesЯпонские исследования
The archaeological direction in the Japanese studies in Russia originated at the end of the 19th century on the basis of the first trips and acquaintance with the antiquities of Japan (M.I. Venyukov, A.V. Grigoriev, I.S. Polyakov, D.M.
A. V. Tabarev
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Zero Shot Recognition with Unreliable Attributes [PDF]

open access: yes, 2016
In principle, zero-shot learning makes it possible to train a recognition model simply by specifying the category's attributes. For example, with classifiers for generic attributes like \emph{striped} and \emph{four-legged}, one can construct a ...
Grauman, Kristen, Jayaraman, Dinesh
core  

Effects of national ecological restoration projects on carbon sequestration in China from 2001 to 2010

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
F. Lu   +33 more
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Vocational Education and Training Workforce [PDF]

open access: yes
This Productivity Commission research report was released on 5 May 2011. This report, the first of a suite of three on the education and training workforce, focusses on the Vocational Education and Training workforce.
Commission, Productivity
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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