Results 81 to 90 of about 763,845 (312)

Journal Staff [PDF]

open access: yes, 2010
In order to handle the increasing costs of healthcare more of the care and monitoring will take place in the patient’s home. It is therefore desirable to develop smaller and portable systems that can record important biosignals such as the electrical ...
Snäll, Jonatan
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Writing strategies employed by advanced learners of English - a questionnaire study [PDF]

open access: yes, 2013
Udostępnienie publikacji Wydawnictwa Uniwersytetu Łódzkiego finansowane w ramach projektu „Doskonałość naukowa kluczem do doskonałości kształcenia”. Projekt realizowany jest ze środków Europejskiego Funduszu Społecznego w ramach Programu Operacyjnego ...
Trendak, Olga
core   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Projekte

open access: yes, 2014
Ausgewählte aktuelle Forschungsvorhaben des IAB im ...
Dieter Wirth   +9 more
openaire   +2 more sources

Weiterentwicklung und Erprobung der Spatendiagnose als Feldmethode zur Bestimmung ökologisch wichtiger Gefügeeigenschaften landwirtschaftlich genutzter Böden [Further Development and Improvement of Spade Diagnosis as Field Method for the Evaluation of Ecological Significant Structure Parameters of Soils under Agricultural Management] [PDF]

open access: yes, 2003
In der vorliegenden Arbeit wird der Vorschlag gemacht, das Bodengefüge aufgrund seiner nach aktuellem Forschungsstand bekannten, vielfältigen Verknüpfung mit der Lebensraum-, Regelungs-, und Produktionsfunktion als geeigneten Indikator für die ...
Beste, Andrea
core  

Teaching writing for high-stakes exams using communicative language teaching methods [PDF]

open access: yes, 2013
Udostępnienie publikacji Wydawnictwa Uniwersytetu Łódzkiego finansowane w ramach projektu „Doskonałość naukowa kluczem do doskonałości kształcenia”. Projekt realizowany jest ze środków Europejskiego Funduszu Społecznego w ramach Programu Operacyjnego ...
Rockenhaus, Melanie
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

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