Results 51 to 60 of about 119,490 (240)

Nuclear weapons and European interests : Discussions in the Assembly of the Western European Union, 1955–1975 [PDF]

open access: yes, 2011
In the 1950s and 1960s the Defence Committee of the Western European Union (WEU) Assembly submitted a series of conspicuous reports on nuclear control issues, culminating in a plea for an Atlantic nuclear force.
Megens, C.M,
core   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Valuation of Economic Risk of Investment Project [PDF]

open access: yes, 2012
Cílem diplomové práce je přiblížení problematiky rizikovosti investičních projektů a řešení situací zohledňujících tato rizika. V práci jsou popsány druhy rizika, jejich klasifikace, metody jeho určování, jeho analýzy a následného zpracování. V praktické
Heringová, Tereza
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Biodynamic approaches in research and development [PDF]

open access: yes, 1999
The paper deals with particular aspects of biodynamics in research and development. It describes the basic background (anthroposophy), the biodynamic preparations with respect to research questions, the need for education and training is pointed out.
Raupp, Dr Joachim
core  

The development of the professionalism of adult educators: a biographical and learning perspective [PDF]

open access: yes, 2011
To investigate the development of the professionalism of adult educators, we compare individuals’ narratives of their professional work at different times in their biographies. Using data from a qualitative longitudinal study, the paper includes two case
Hof, Christiane, Maier-Gutheil, Cornelia
core   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Learning with worked-out problems in Manufacturing Technology: The effects of instructional explanations and self-explanation prompts on acquired knowledge acquisition, near and far transfer performance [PDF]

open access: yes, 2011
In the present research, two different explanatory approaches – namely, instructional explanation and self-explanation prompts – were applied in worked-out-problem-based learning (learning with worked-out problems) in a computer-assisted instructional ...
Lai, Chee Sern   +2 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

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