Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Does timing of physical exercise after reconstructive prolapse surgery matter? [PDF]
Braz J Phys TherMicussi M +3 more
europepmc +1 more source
Testicular torsion in foals and stallions
Equine Veterinary Education, EarlyView.Summary Testicular torsion is a rare condition in horses characterised by a change in the position of the testis due to the testicular mesentery twisting around its own axis; it can occur both when the testis is still in the abdominal cavity and when it has descended into the scrotum.
C. P. Bartmann
wiley +1 more source
Connective tissue and genetics in the pathogenesis of rectal prolapse: A scoping review. [PDF]
Colorectal DisDavenport M +9 more
europepmc +1 more source
Standing diverticulectomy for treatment of a pulsion oesophageal diverticulum in a horse
Equine Veterinary Education, EarlyView.Summary A 7‐year‐old Quarter Horse gelding was presented for evaluation and treatment of a pulsion oesophageal diverticulum diagnosed 8 months earlier following repeated episodes of oesophageal obstruction. Diagnostic imaging—including cervical radiographs, ultrasound and endoscopy—was used to diagnose and evaluate the lesion and guide surgical ...
Y. Tanaka, D. Major
wiley +1 more source
High versus low take-off rectal prolapse: Outcomes of tailored surgery: Letter to the editor. [PDF]
Colorectal DisBrusciano L, Docimo L.
europepmc +1 more source
Equine Veterinary Education, EarlyView.Summary A 21‐year‐old gelding, with a history of equine recurrent uveitis, was presented for a chronic nonhealing corneal ulcer. Ophthalmic examination of the right eye revealed a deep corneal ulcer, with the presence of corneal neovascularisation, mild diffuse corneal oedema and hypopyon. Additionally, the gelding was blind from the affected eye.
M. van Heule +5 more
wiley +1 more source
Journal of Cardiovascular Electrophysiology, EarlyView.In anticoagulated atrial fibrillation, residual ischemic stroke risk persists despite guideline‐directed therapy. In this single‐center cohort, an enlarged index outpatient left atrial diameter independently predicted stroke and improved risk stratification when added to CHA2DS2‐VA (CHA2DS2‐VALa), supporting a simple, clinically implementable ...
Sefa Erdi Ömür +7 more
wiley +1 more source
Identification and Treatment of Anorexia Nervosa in Women With Perimenopause
Journal of Midwifery &Women's Health, EarlyView.Abstract Disordered eating is a common problem that midwives will encounter as frontline primary care providers. Anorexia nervosa (AN) is a form of disordered eating that results in chronic starvation state, creating significant risk of morbidity and mortality to the patient. AN is traditionally considered a disorder of adolescence and young adulthood;
Janell Senda +2 more
wiley +1 more source
Kissing Rectal Ulcers With Associated Occult Rectal Mucosal Prolapse: A Distinct Endoscopic Presentation of Solitary Rectal Ulcer Syndrome in an HIV Positive Patient With Comprehensive Infectious Exclusion. [PDF]
Case Rep Gastrointest MedGanju N +6 more
europepmc +1 more source