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Proliferative vitreoretinopathy and chemotherapeutic agents
Survey of Ophthalmology, 1985Proliferative vitreoretinopathy (PVR) is a disease process that occurs in eyes with rhegmatogenous retinal detachments and accounts for the majority of failures following retinal detachment surgery. PVR involves the uncontrolled proliferation of non-neoplastic cells capable of forming membranes, which may occur on either surface of the retina or along ...
Joel A. Schulman, Gholam A. Peyman
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Interventions for Proliferative Vitreoretinopathy
JAMA OphthalmologyClinical QuestionWhat is the efficacy of pharmacologic interventions in preventing proliferative vitreoretinopathy?Bottom LineThere is limited high-quality evidence to support currently available pharmacological options for prevention of proliferative vitreoretinopathy.
Wilson X, Wang+2 more
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Surgical Results for Proliferative Vitreoretinopathy [PDF]
We reviewed 88 consecutive eyes that underwent vitrectomy for retinal detachment with proliferative vitreoretinopathy (PVR) and were followed a minimum of six months. A primary goal of the surgery was the meticulous trimming of the vitreous base in hopes of decreasing the incidence of postoperative reproliferation and anterior PVR.
D. Madeira+3 more
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Spontaneous resolution of proliferative vitreoretinopathy
Acta Ophthalmologica, 1992Abstract A case of proliferative vitroretinopathy that spontaneously regressed, leading to reattachment of the retina, is presented. The importance of such a spontaneous resolution in terms of understanding the pathogenesis, and planning a treatment, is discussed.
Anat Loewenstein+3 more
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Risk factors for proliferative vitreoretinopathy
Progress in Retinal and Eye Research, 1998Proliferative vitreoretinopathy (PVR) is one of the major causes of failure in retinal detachment surgery. To prevent PVR, it is necessary to determine factors predisposing its development. In primary PVR, large retinal tears, long duration of retinal detachment, vitreous hemorrhages, aphakia and choroidal detachment were demonstrated as clinical risk ...
Manabu Mochizuki+2 more
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Current Management of Proliferative Vitreoretinopathy
Seminars in Ophthalmology, 1995The recognition of APVR and its dissection, along with the use of perfluorocarbon liquids, has greatly improved the success rate in surgery for severe PVR. In reviewing our first 71 cases using these techniques, 75% were attached with one operation and 90% were attached with one or more operations.
H. M. Lambert+3 more
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Management of Proliferative Vitreoretinopathy
2015Proliferative vitreoretinopathy (PVR) is the clinical syndrome associated with retinal traction and detachment in which cells with proliferative potential multiply and contract on retinal surfaces and in the vitreous compartment. PVR presents with a broad spectrum of severity ranging from subtle retinal wrinkling to a total rigid retinal detachment ...
D. Velázquez-Villoria, J. García-Arumi
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RUBEOSIS OF THE IRIS IN PROLIFERATIVE VITREORETINOPATHY
RETINA, 1996The authors report the findings and clinical course of rubeosis in patients with essentially reattached retinas after vitrectomy and silicone oil for proliferative vitreoretinopathy (PVR).From 1989 on, the authors prospectively noted all patients with rubeosis and with attached retina posterior to the buckle after vitrectomy and silicone oil for PVR as
Diane A. E. Mertens+4 more
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Pharmacological therapy for proliferative vitreoretinopathy
Graefe's Archive for Clinical and Experimental Ophthalmology, 1986We developed an animal model in the rabbit eye with intravitreally injected heterotransplanted bovine retinal pigment epithelial cells to test a pharmacological agent which would reduce extracellular matrix formation. Results with 20 and 60 micrograms of cis-hydroxyproline showed a 48% decrease in the rate of traction retinal detachments.
R J Ballou, A D Weinsieder, N D Radtke
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