Results 121 to 130 of about 6,153 (299)

Selection for high and low prolificacy in Cambridge sheep

open access: yes, 1997
Previous reports have suggested the presence of a major gene influencing prolificacy in the Cambridge sheep breed. To estimate the effect of such a gene, high and low prolificacy groups were established in a Cambridge sheep flock between lambing years ...
I. Ap Dewi   +3 more
core   +1 more source

ОЦЕНКА НА ПРОДУКТИВНИТЕ ПРИЗНАЦИ НА ОВЦЕ ОТ СИНТЕТИЧНА ПОПУЛАЦИЯ БЪЛГАРСКА МЛЕЧНА В ЗАВИСИМОСТ ОТ ЛИНЕЙНАТА ИМ ПРИНАДЛЕЖНОСТ

open access: yesЖивотновъдни науки, 2013
The aim of the present study was to evaluate the parameters of the productive traits as affected by lineage in sheep from the Synthetic Population Bulgarian Milk (SPBM). It assigned 851 ewes borne during the period 2004-2008 on the experi¬mental farm of
НЕВЯНА СТАНЧЕВА
doaj  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Selection for prolificacy in Finnsheep and in Norwegian sheep

open access: yesAgricultural and Food Science, 1988
Litter size (LS) at birth and other production traits were recorded for Finnsheep (F), Norwegian(N) breeds Dala (D), Steigar (St) and Spael (Sp), for N sheep crossed with 1/4 F and ½ F and for a group of sheep established by collecting offspring of highly prolific N(N+) ewes. The N breeds and the ¼ F group were part of the national breeding scheme.
openaire   +4 more sources

Growth Dynamics of Lithuanian Blackface Lambs: Role of Crossbreeding with German Blackheaded Mutton Rams, Sex and Seasonality

open access: yesAgriculture
Crossbreeding is widely used to improve livestock performance, combining favorable breed traits through additive effects while maintaining genetic diversity.
Rūta Šveistienė, Violeta Razmaitė
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

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