Results 81 to 90 of about 6,153 (299)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Search of evidence of a major gene for prolificacy in four Spanish sheep breeds
, 2012 In sheep have identified ten alleles are associated with increased ovulation rate and prolificacy. The use of these or other possible mutations may be an important tool to increase the genetic progress of the prolificacy.
Muñoz, Rubén, Jurado, Juán José
core
Genetic control of reproductive plasticity through prolificacy and tillering in maize
Context Prolificacy and tillering have not been traditional targets of maize breeding programs. As agriculture expands into marginal environments, these traits may become increasingly relevant under low plant ...
Ignacio R. Hisse +7 more
core +1 more source
, 2012 The Mediterranean Iberian pigs show a clear predisposition to obesity, due to gene polymorphisms for leptin receptors, and a lower prolificacy when compared with lean breeds.
Gonzalez-Añover, P. +7 more
core +1 more source
Effect of Mummified Fetuses on the Prolificacy of Holsteins
Journal of Dairy Science, 1957 Summary Over a 30-year period in a closely observed breeding herd, 29 of 2,607 cows produced 32 mummified fetuses. This represented 1.1% of the cows and 0.43% of the parturitions. The range in gestation was 131 to 342 days (mean = 215 days). Cows having mummified fetus were considerably above herd average in number of reproductive periods and in ...
R.E. Erb, R.A. Morrison
openaire +1 more source
Identification of two major genes affecting prolificacy in the French Noire du Velay sheep
, 2017 Identification of two major genes affecting prolificacy in the French Noire du Velay sheep. 36.
Bodin, Loys +4 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
, 2018 Reproductive ability, especially prolificacy, impacts sheep profitability. Hu sheep, a unique Chinese breed, is recognized for its high prolificacy (HP), early sexual maturity, and year-round estrus.
Tingting Zhang +9 more
core +1 more source
Potential Candidate Genes Associated with Litter Size in Goats: A Review
AnimalsThis review examines genetic markers associated with litter size in goats, a key reproductive trait impacting productivity in small ruminant farming. Goats play a vital socioeconomic role in both low- and high-income regions; however, their productivity ...
Wenting Chen +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source