Results 131 to 140 of about 209,035 (336)

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

A case of ventricular fibrillation as a consequence of capecitabine-induced secondary QT prolongation: A case report [PDF]

, 2017
Kazuto Hayasaka, Masateru Takigawa, Atsushi Takahashi, Taishi Kuwahara, Kenji Okubo, Yasuaki Tanaka, Toru Misawa, Masafumi Mizusawa, Yosuke Yamakami, Keisuke Kojima, Yuichiro Sagawa, Keiichi Hishikari, Kazuya Yamao, Emiko Nakashima, Jun Nakajima, Shigeki Kimura, Katsumasa Takagi, Hiroyuki Hikita, Mitsuaki Isobe   +18 more
openalex   +1 more source

Prolongation of survival time and improvement of the quality of life after treatment with irinotecan liposomal in the patient with metastatic pancreatic adenocarcinoma

, 2021
Wojciech Rogowski, Przemysław Będkowski   +1 more
openalex   +2 more sources

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

QT Prolongation Due to Organophosphate Poisoning [PDF]

, 2000
Ayc Siu, Л М Цой, Wcb Lo, Cch Chung
openalex   +1 more source

Prolonged Weightlessness [PDF]

BMJ, 1970
openaire   +2 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Drug-Induced QT Prolongation: Individual Susceptibility and Regulatory Issues Related to Safety Pharmacology 5. QT Interval: Gender and Other Affecting Factors in the Clinical Setting

, 2006
Tetsunori Saikawa
openalex   +2 more sources

START-3 Treaty prolongation: views of the U.S. political elites and experts

, 2020
Maria Solyanova
openalex   +1 more source