Results 181 to 190 of about 209,035 (336)

A review of clinical pharmacology considerations in antibody-drug conjugates approved by the US Food and Drug Administration between 2000 and 2025. [PDF]

Transl Clin Pharmacol
Koo S, Kim CY, Lim JH, Lee E, Kim IY, Shin YG, Moon H.   +6 more
europepmc   +1 more source

Drug-induced QTc-prolongation : risk management in a community pharmacy

, 2017
Eline Vandael, Veerle Foulon
openalex   +1 more source

Event-Related Potential Prolongation in Alzheimer's Disease Signifies Frontal Lobe Impairment: Evidence From SPECT Imaging [PDF]

, 1996
Deirdre O’Mahony, J. Coffey, Joseph Murphy, Neil O’Hare, Derek A. Hamilton, Michael J. Rowan, P. Freyne, J.B. Walsh, Davis Coakley   +8 more
openalex   +1 more source

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source

QT interval prolongation: clinical assessment, risk factors and quantitative pharmacological considerations. [PDF]

J Pharmacokinet Pharmacodyn
Gotta V, Donner B.
europepmc   +1 more source

Correlation between the Severity of Liver Cirrhosis (Chil-Pugh Score) and QTc Interval Prolongation

, 2012
Rachmad Aji Saksana, Putut Bayupurnama, Fahmi Indrarti, Neneng Ratnasari, Sutanto Maduseno, Catharina Triwikatmani, Siti Nurdjanah   +6 more
openalex   +2 more sources

Drug-induced QT interval prolongation and torsades de pointes

Canadian Pharmacists Journal / Revue des Pharmaciens du Canada, 2016
J. Tisdale
semanticscholar   +1 more source

Impact of Stress‐Induced Hyperglycemia on In‐Hospital Medical Complications in Patients With Acute Stroke: From a Large‐Scale Nationwide Longitudinal Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song, Yi Ju, Hongqiu Gu, Zhikai Zhu, Zixiao Li, Qian Zhang, Xingquan Zhao   +6 more
wiley   +1 more source

Prescribed drugs and comorbidities as risk factors for Torsades de Pointes arrhythmia: a Swedish population-based cohort study. [PDF]

Eur J Clin Pharmacol
Andersson ML, Fastbom J, Danielsson B, Wikström E, Dahl ML, Nowinski K.   +5 more
europepmc   +1 more source

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source