Low to moderate-dose off-label use of second-generation antipsychotics seems to be safe in the light of cardiac adverse effects in child psychiatric patients. [PDF]
Kakko K +3 more
europepmc +1 more source
Prolongation of renal homograft survival by inhibition of the afferent arc of the immune response
P. J. Cleveland +3 more
openalex +1 more source
Objectives Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged 70 and older.
Amanda J Rickard +15 more
wiley +1 more source
Delayed Repolarization Caused by hERG Block With Different Drug Modalities Can Be Detected in Stem Cell-Derived Cardiomyocytes: Incubation Time Matters. [PDF]
Qu Y +6 more
europepmc +1 more source
Chronic Opioids in Gout: A Matched Cohort Study from the Veteran's Health Administration
Objective Though used frequently to treat flare, risk of chronic opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed chronic opioids over time.
Lindsay N. Helget +7 more
wiley +1 more source
No Evidence of QTc Interval Prolongation With Baxdrostat Treatment: Concentration-QTc Modeling Assessment. [PDF]
Sunnåker M +7 more
europepmc +1 more source
PROLONGATION OF KIDNEY SURVIVAL DURING AND AFTER CYGLOSPORIN A THERAPY
D C Dunn +3 more
openalex +1 more source
Objective The aim of this study was to investigate the cost‐effectiveness of low‐dose colchicine prophylaxis for preventing gout flares when starting allopurinol using the “start‐low go‐slow” approach. Methods Participants with gout, fulfilling the American College of Rheumatology recommendations for starting urate‐lowering therapy and with serum urate
Yana Pryymachenko +4 more
wiley +1 more source
Decoding Silent Signals: A Systematic Review of ECG and the Quest for an Early Diagnosis of Cirrhotic Cardiomyopathy. [PDF]
Neelakantan Ramaswamy S +6 more
europepmc +1 more source

