Results 161 to 170 of about 87,591 (293)

Mechanosensitive Piezo1 Channels Mediate Diaphragm Fibrosis Induced by Prolonged Mechanical Ventilation. [PDF]

J Cachexia Sarcopenia Muscle
Xie D, Xiao Y, Li X, Sun B, Feng J, Jia J, Li J, Wang Y, He F, Liu L.   +9 more
europepmc   +1 more source

CAN WE REVERSE NEGATIVE IMPACT OF PROLONGED MECHANICAL VENTILATION ON RESPIRATORY MUSCLES?

, 2017
BACKGROUND: Prolonged mechanical ventilation although saving lives, can have decremental eff ect on repiratory muscles, mainly diaphragm. Th e aim of this article is to summarize the mechanisms of respiratory muscle atrophy and possible interventions
Camlek, Luka, Luka Camlek
core  

Lung maneuvers of large amplitudes for probing physiological alterations in mouse models of asthma

Animal Models and Experimental Medicine, EarlyView.
Lung maneuvers of small amplitudes, such as the ones performed in oscillometry, are the current gold standard to probe lung mechanics in animals, but they are insensitive to detect baseline physiological alterations in mouse models of asthma. Herein, lung maneuvers of different amplitudes were compared in two mouse models of asthma.
Magali Boucher, Cyndi Henry, Marie‐Josée Beaulieu, Andrés Rojas‐Ruiz, Ynuk Bossé   +4 more
wiley   +1 more source

Respiratory Microbiome in Elderly Patients on Prolonged Mechanical Ventilation: A Prospective Multi-Center Observational Study. [PDF]

Clin Interv Aging
Wang Y, Wu J, Wang Y, Jiang W, Wang D, Zhao J, Qin X, Yuan Y, Zhang H, Wang J, Zhen J, Du Y, Mu X, Li L, Wang T, Zou L, Fang X, Sun B, Li H.   +18 more
europepmc   +1 more source

PROLONGED MECHANICAL VENTILATION IN ACUTE RESPIRATORY DISTRESS SYNDROME

Purpose: Trajectory of acute respiratory distress syndrome (ARDS) spans from rapidly improving cases to cases receiving prolonged mechanical ventilation (PMV).
Papathanakos, Georgios, Giannakoulis, Vassilis G., Papoutsi, Eleni, Thompson, B. Taylor, Koulouras, Vasilios, Siempos, Ilias I., Andrianopoulos, Ioannis   +6 more
core  

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Risk factors for prolonged mechanical ventilation in critically ill patients with ischemic stroke. [PDF]

Neurotherapeutics
Luo J, Zhang C, Deng R, Liu L, He C, Zhang R, Zhang J, Lu J, Shan Y, Zhang W, Fang B.   +10 more
europepmc   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

nSOFA scores predict prolonged mechanical ventilation in neonatal respiratory distress syndrome: a retrospective cohort study. [PDF]

BMC Pediatr
Wang L, Duan Y, Zhang X, Xie L, Liu H, Liu Y.   +5 more
europepmc   +1 more source

Establishment of a chronic aspiration pneumonia mouse model using oropharyngeal aspiration of food suspension

Animal Models and Experimental Medicine, EarlyView.
Four aspiration methods (UV, IN, IT, and OA) were compared, and OA was identified as the most effective delivery technique. A chronic aspiration pneumonia model was then established through repeated OA of food suspension or gastric contents. Integrated analyses, including micro‐CT, histopathology, cytokine profiling, and RNA sequencing, revealed ...
Qianwen Li, Fansen Lin, Hongzhi Gao, Yun Zhao, Yuqi Liu   +4 more
wiley   +1 more source