Results 271 to 280 of about 222,440 (323)

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić   +4 more
wiley   +1 more source

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić   +4 more
wiley   +1 more source

Effect of Atypical Sleep EEG Patterns on Weaning From Prolonged Mechanical Ventilation. [PDF]

open access: yesChest
Shaikh H   +6 more
europepmc   +1 more source

Prolonged Mechanical Ventilation in Children: Review of the Definition

Pediatric Critical Care Medicine, 2021
Supplemental Digital Content is available in the text. OBJECTIVES: To review existing definitions of prolonged mechanical ventilation in children. DESIGN: Review of the literature. SETTING: Not applicable.
J. Colleti   +3 more
semanticscholar   +1 more source

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