Results 261 to 270 of about 113,542 (365)

Various surgical techniques result in different outcomes for full extensor mechanism ruptures following total knee replacement: A systematic review by the European Knee Associates (ESSKA‐EKA)

Knee Surgery, Sports Traumatology, Arthroscopy, Volume 34, Issue 2, Page 586-595, February 2026.
Abstract Purpose Extensor mechanism (EM) ruptures after total knee arthroplasty (TKA) are rare but lead to substantial functional impairment and morbidity. Treatment remains challenging due to the diversity of surgical techniques and the limited number of comparative studies.
Bruno Violante, Riccardo Compagnoni, Artur Kroell, Michael Engl, Octav Russu, George Mihai Avram, Sarper Gursu, Elvire Servien, Francesco Puglia, Pietro Simone Randelli, Reha Tandogan, Michael T. Hirschmann, European Knee Associates (EKA)   +12 more
wiley   +1 more source

QT interval prolongation: clinical assessment, risk factors and quantitative pharmacological considerations. [PDF]

J Pharmacokinet Pharmacodyn
Gotta V, Donner B.
europepmc   +1 more source

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian, Jun Ge, Ni Fan, Zheng Sun, Chengcheng Zhao, Yujiao Sun, Yingpeng Li, Yunfei Li, Hui Fu   +8 more
wiley   +1 more source

Loperamide-Induced Ventricular Arrhythmia and Seizures. [PDF]

JACC Case Rep
Lateef A, Vardar U, Sanclemente D, Lee B, Pasupula D, Tseng AS, van Niekerk CJ.   +6 more
europepmc   +1 more source

Model‐Based Meta‐Analysis of the Relationship Between Pioglitazone and Histological Outcomes in Metabolic Dysfunction‐Associated Steatohepatitis Patients

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Given the high prevalence of the population who have metabolic dysfunction‐associated steatohepatitis (MASH), interest is growing in MASH‐targeted treatments. However, currently, there has been only one regulatory approved drug for MASH (Rezdiffra).
Quyen Thi Tran, Tham Thi Bui, Lien Thi Ngo, Bo Ram Yang, In‐Hwan Baek, Van Hung Nguyen, Kyung Ae Lee, Hwi‐yeol Yun, Jung‐woo Chae, Soyoung Lee, Jae Hyun Kim, Woojin Jung   +11 more
wiley   +1 more source

Diagnosis of a Neonate With Long QT Syndrome and Severe Complications Delayed due to an Unrecognized Familial History. [PDF]

Case Rep Pediatr
Kawabata K, Chida-Nagai A, Takeda K, Honjo R, Sasaki D, Yamazawa H, Kaneshi Y.   +6 more
europepmc   +1 more source

Managing Drug–Drug Interactions Involving the Non‐Prescription Opioid Loperamide Through Physiologically Based Pharmacokinetic Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Loperamide is a widely used nonprescription peripherally acting opioid indicated for diarrhea. Loperamide undergoes extensive first‐pass metabolism, primarily by cytochrome (CYP) 3A and CYP2C8, with minor contributions from CYP2B6 and CYP2D6, and intestinal efflux by P‐glycoprotein (P‐gp).
Zhu Zhou, Garrett R. Ainslie, Mengyao Li, Jean Dinh, Maciej J. Zamek‐Gliszczynski, Ping Zhao, Mary F. Paine   +6 more
wiley   +1 more source

Prolonged QT Interval and the BMI, Systolic BP and HDL-Cholesterol in Type 2 Diabetic Patients.

, 2005
Chunggu Cho, Hye Jung No, Hyo Jeong Oh, Bong Joon Yang, Ha Young Kim, Byoung Hyun Park   +5 more
openalex   +1 more source

Suspected pro‐arrhythmic effects of flecainide and the limitations of in‐hospital short‐duration electrocardiography in detecting ventricular arrhythmia burden in a dog with dilated cardiomyopathy

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 10‐year‐old, female, spayed Pitbull mix presented for evaluation of an arrhythmia. Echocardiography revealed enlargement of all cardiac chambers and decreased left ventricular systolic function. Electrocardiography demonstrated isolated, ventricular premature complexes.
Nathan Mitchell, Tamilselvam Gunasekaran, Robert Sanders, Joanne DeSana   +3 more
wiley   +1 more source

A MATLAB Algorithm to Automatically Estimate the QT Interval and Other ECG Parameters and Validation Using a Machine Learning Approach in Congenital Long-QT Syndrome. [PDF]

J Cardiovasc Transl Res
Tzvi-Minker E, Dittmann S, Rickert C, Keck A, Schulze-Bahr E.   +4 more
europepmc   +1 more source