BACKGROUND: Arsenic trioxide (ATO) regimen is now the standard of care for acute promyelocytic leukemia (APL). The complete remission and possible cure are reported to be 50%–80% of APL patients.
Aseel Abd Ul Sahib Hassan +1 more
doaj +1 more source
Haloperidol affects coupling between QT and RR intervals in guinea pig isolated heart
Prolonged QT interval is an independent risk factor for development of ventricular arrhythmias. Haloperidol is one of the drugs inducing QT prolongation.
Petr Vesely +8 more
doaj +1 more source
In this numerical study, we investigate the role of intrinsic heterogeneities of cardiac tissue due to M cells in the generation and maintenance of reentrant excitations using the detailed Luo-Rudy dynamic model. This model has been extended to include a
Cherry E. M. +3 more
core +1 more source
Electrocardiographic manifestation of cardiac repolarization dispersion [PDF]
Alterations of repolarization heterogeneity in the heart have been established as anAlterations of repolarization heterogeneity in the heart have been established as ...
Sedova Ksenia
core
Comprehensive translational assessment of human-induced pluripotent stem cell derived cardiomyocytes for evaluating drug-induced arrhythmias [PDF]
Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM) hold promise for assessment of drug-induced arrhythmias and are being considered for use under the comprehensive in vitro proarrhythmia assay (CiPA).
Blinova, Ksenia +17 more
core +1 more source
DISPERSIÓN DEL INTERVALO QT CORREGIDO EN LA EVOLUCIÓN DE PACIENTES CON SÍNDROMES CORONARIOS AGUDOS / Corrected QT interval dispersion in the evolution of patients with acute coronary syndromes [PDF]
Introduction and Objectives: Acute myocardial infarc-tion remains a major challenge for health systems. In the classic concept of the ischemic cascade, the earliest event is the QT interval prolongation, which was previously reported in patients with ...
Carlos J. Fabelo Mora +5 more
doaj
International criteria for electrocardiographic interpretation in athletes: Consensus statement. [PDF]
Sudden cardiac death (SCD) is the leading cause of mortality in athletes during sport. A variety of mostly hereditary, structural or electrical cardiac disorders are associated with SCD in young athletes, the majority of which can be identified or ...
Aagaard +198 more
core +2 more sources
Modelling the effects of disopyramide on short QT syndrome variant 1 in the human ventricles [PDF]
The short QT syndrome (SQTS) is a recently identified genetic disorder associated with ventricular and/or atrial arrhythmias and increased risk of sudden cardiac death.
Benson, AP +4 more
core +3 more sources
Itraconazole-induced Torsade de Pointes in a patient receiving methadone substitution therapy [PDF]
Issues. Methadone, a pharmacological agent used to treat heroin dependence is relatively safe, but may cause cardiac arrhythmias in the concurrent presence of other risk factors. Approach and Key Findings.
Narayanan, S. +2 more
core
Methadone and Corrected QT Prolongation in Pain and Palliative Care Patients: A Case–Control Study [PDF]
Background: Methadone (ME) is commonly used in pain and palliative care (PPC) patients with refractory pain or intolerable opioid adverse effects (AEs).
Brown, Jack +3 more
core +2 more sources

