Results 91 to 100 of about 684,699 (287)

Simulations of Prominence Formation in the Magnetized Solar Corona by Chromospheric Heating

, 2012
Starting from a realistically sheared magnetic arcade connecting chromospheric, transition region to coronal plasma, we simulate the in-situ formation and sustained growth of a quiescent prominence in the solar corona.
Amari, Antiochos, Bommier, Colgan, Hillier, Karpen, Kippenhahn, Kuperus, Lionello, Mandrini, Mok, Mok, Petrie, Xia   +13 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Development of the Face

Siriraj Medical Journal, 2006
The human face develops between the fourth and eighth week after conception. Its development can be traced to five facial primordia appearing around the stomodeum in the fourth week.
Jantima Roongruangchai, Kajee Pilakasiri, Sompis Imjai   +2 more
doaj  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Energy release in the solar atmosphere from a stream of infalling prominence debris

, 2017
Recent high-resolution and high-cadence EUV imaging has revealed a new phenomenon, impacting prominence debris, where prominence material from failed or partial eruptions can impact the lower atmosphere, releasing energy.
Gilbert, Holly R., Inglis, Andrew R., Ofman, Leon   +2 more
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Differential object marking in Western Malayo-Polynesian symmetrical voice languages

Linguistic Typology
Differential object marking (DOM) is known from a great variety of language families. We present data suggesting that, contrary to what is suggested in recent typological surveys, DOM is also a widespread phenomenon in Austronesian symmetrical voice ...
Bonmann Svenja, Riesberg Sonja, Himmelmann Nikolaus P.   +2 more
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Propagating Waves Transverse to the Magnetic Field in a Solar Prominence

, 2013
We report an unusual set of observations of waves in a large prominence pillar which consist of pulses propagating perpendicular to the prominence magnetic field.
Knizhnik, K., Kucera, T. A., Lopez-Ariste, A., Luna, M., Schmieder, B., Toot, D.   +5 more
core   +2 more sources