Results 31 to 40 of about 183,243 (303)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Transgène et la thérapie génique
Socio, 2019 By retracing the history of the attempt of the French biotech company Transgene to develop gene therapy products, this article aims at deciphering the mechanisms that allowed Transgene, on the basis of a discourse of promises, to sustain an enormous ...
Annick Jacq
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Native promises vs Bluebird promises in NODE.JS
Adaptivni Sistemi Avtomatičnogo Upravlinnâ, 2019 In this article the main point is in comparing of two ways to work with an asynchronous code in Node.js. Because Node.js is native asynchronous this problem is very important.
Y. Timoshin, B. Barna
doaj +1 more source
Promises, Offers, Requests, Agreements
Ergo, An Open Access Journal of Philosophy, 2023 If I promise to pick you up at the airport, I thereby become obligated to do so. But this is not the only way I could undertake this obligation. If I offer to pick you up, and you accept my offer, I become obligated to pick you up in much the same way. I
Brendan de Kenessey
doaj +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
, 2016 The notion of the economically insecure ‘Precariat’ class is the focus of enquiry by numerous philosophers, journalists, writers, and artists seeking to examine the social conditions imposed by neoliberal politics.
McKewen, Daniel
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source