Results 241 to 250 of about 1,804,103 (360)

A unified computational framework for quantitative design and optimization of transcriptional regulation across bacterial species. [PDF]

Nucleic Acids Res
Wang T, Xie R, Ma Z, Chen Y.
europepmc   +1 more source

Additional file 6: Table S15. of Comprehensive promoter level expression quantitative trait loci analysis of the human frontal lobe

, 2016
Cornelis Blauwendraat, Margherita Francescatto, J. Raphael Gibbs, Iris E. Jansen, Javier Simรณn-Sรกnchez, Dena Hernandez, Allissa Dillman, Andrew Singleton, Mark Cookson, Patrizia Rizzu, Peter Heutink   +10 more
openalex   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Antisense transcription can induce expression memory via stable promoter repression. [PDF]

Genome Biol
Mutzel V, Schwämmle T, Oeverdieck S, Librenjak L, Boesen B, Bothe M, Gjaltema RAF, Dunkel I, Noviello G, Schulz EG.   +9 more
europepmc   +1 more source

DoOP chordate v1.4 dataset, motif data for 1000 nt promoter regions

, 2015
Endre Sebestyén, Tamás B Pálfy, Tibor Nagy, Gábor Tóth, Endre Barta   +4 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Comparative TSS-seq analysis among natural variations of <i>Arabidopsis</i> reveals the genetic stability of genic and nongenic promoters. [PDF]

NAR Genom Bioinform
Sugekawa K, Ezeh OS, Yamamoto YY.
europepmc   +1 more source

RGS3 functions as a tumor promoter by facilitating the activation of the TGF-β signaling pathway and promoting EMT in ovarian cancer. [PDF]

Jinhua Zhou, Zizhao Wang, Huating Sun, Shunpeng Zhu, Fang Wang, Quan Li   +5 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Activation of bacterial transcription by distortion of promoter base pairing. [PDF]

Nucleic Acids Res
Klimova KM, Forrest D, Sharma P, Haycocks JRJ, Grainger DC.   +4 more
europepmc   +1 more source