Results 251 to 260 of about 2,113,360 (356)

Extensive Promoter-Centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation

Cell, 2012
Guoliang Li, Xiaoan Ruan, Raymond K. Auerbach, K. Sandhu, Meizhen Zheng, Ping Wang, H. Poh, Yufen Goh, Joanne Lim, Jingyao Zhang, Hui Shan Sim, Su Qin Peh, F. Mulawadi, C. T. Ong, Y. Orlov, Shuzhen Hong, Zhizhuo Zhang, S. Landt, D. Raha, G. Euskirchen, Chia-Lin Wei, W. Ge, Huaien Wang, Carrie A. Davis, Katherine I. Fisher-Aylor, A. Mortazavi, M. Gerstein, T. Gingeras, B. Wold, Y. Sun, M. Fullwood, E. Cheung, E. Liu, W. Sung, M. Snyder, Y. Ruan   +35 more
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Association of TERT promoter mutation with oral squamous cell carcinoma: a systematic review and meta-analysis. [PDF]

Sci Rep
Yuwanati M, Sarode S, Sarode G, Gadbail A, Gondivkar S, Chaurasia A, Dwivedi D, Delgadillo-Barrera S.   +7 more
europepmc   +1 more source

DNA sequence of the araBAD promoter in Escherichia coli B/r.

, 1978
Lawrence Greenfield, Thomas C. Boone, Gary Wilcox   +2 more
openalex   +1 more source

qin101: Promoter mutation which allows the constitutive expression of the late genes [PDF]

, 1979
C. Dambly, M Delstanche, Anne‐Marie GATHOYE   +2 more
openalex   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Exploring the association between serotonin transporter promoter region methylation levels and depressive symptoms: a systematic review and multi-level meta-analysis. [PDF]

Transl Psychiatry
Javelle F, Dao G, Ringleb M, Pulverer W, Bloch W.   +4 more
europepmc   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Predicting gene expression changes from chromatin structure modification. [PDF]

NPJ Syst Biol Appl
Senapati S, Irshad IU, Sharma AK, Kumar H.   +3 more
europepmc   +1 more source

Nucleotide Sequence in the Promoter Region of the Escherichia coli Tyrosine tRNA Gene

, 1974
Takao Sekiya, H. Gobind Khorana
openalex   +1 more source