Results 261 to 270 of about 1,389,605 (343)

The latent cis-regulatory potential of mobile DNA in Escherichia coli. [PDF]

Nat Commun
Fuqua T, Wagner A.
europepmc   +1 more source

Modification of Recombination-based GATEWAY^TM Binary Destination Vector with Novel Promoter for <i>Agrobacterium</i>-mediated Transformation of Rice

, 1970
Md. Rakibul Islam, Richard Malo, Rumana S Tammi, Sharmin Jahan, Lisa Parvin, Zeba I. Seraj   +5 more
openalex   +2 more sources

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

High-throughput metabolic engineering of <i>Yarrowia lipolytica</i> through gene expression tuning. [PDF]

Proc Natl Acad Sci U S A
Jiang W, Wang S, Ahlheit D, Fumagalli T, Yang Z, Ramanathan S, Jiang X, Weber T, Dahlin J, Borodina I.   +9 more
europepmc   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

NAC1/ACOX2 Axis as a Novel Therapeutic Target for Endometriosis-Related Ovarian Neoplasms. [PDF]

Int J Mol Sci
Sonia SB, Nakayama K, Razia S, Nakayama N, Ishikawa M, Yamashita H, Kanno K, Takeshita H, Zahan UF, Sohel HI, Kyo S.   +10 more
europepmc   +1 more source

Translational control of SV40 T antigen expressed from the adenovirus late promoter

, 1983
Carl S. Thummel, Robert Tjian, Shiu Lok Hu, Terri Grodzicker   +3 more
openalex   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

C2H2-type zinc finger protein transcription factor MdZAT1 plays a negative role in anthocyanin biosynthesis in apple. [PDF]

Mol Hortic
Ren Y, Huo W, Wang Z, Liu S, Chen Y, Xu X, Hou H, Dong C, Xu J, Chen M, Zhang Y, Jiang S.   +11 more
europepmc   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source