Results 271 to 280 of about 1,804,103 (360)

Bacteria sense the antibiotic rifampicin through a widespread dual-promoter based alarm system. [PDF]

Nucleic Acids Res
Sudzinová P, Knežová Balgová T, Schwarz M, Juříková Mikesková K, Hegrová K, Vítovská D, Rawat P, Bobková Š, Kočárková V, Natarajan S, Pospíšilová D, Křenková A, Hubálek M, Halada P, Barvík I, Koval' T, Dohnálek J, Wiedermannová J, Šanderová H, Krásný L.   +19 more
europepmc   +1 more source

Triflic acid catalyzed isobutane alkylation with trifluoroethanol as a promoter

, 2011
Hailing Ren, Guoying Zhao, Suojiang Zhang, Peng Cui, Jun Huang   +4 more
openalex   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Single Nucleotide Polymorphisms in the Promoter Region of <i>MyoG</i> Gene Affecting Growth Traits and Transcription Factor Binding Sites in Guizhou White Goat (<i>Capra hircus</i>). [PDF]

Genes (Basel)
Song X, Long H, Meng J, Zhao Y, Wu Z, An Q.   +5 more
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Correction: Epigenetic activation of CD274/PD-L1 by the MSL complex expands its role beyond dosage compensation. [PDF]

Front Immunol
Wen A, Feng X, Li Y, Cui X, Zou Q, Cai Y, Jin J, He Y.   +7 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Identification of strong constitutive promoters in Burkholderia stagnalis TBRC 18363 for activating natural product production in Gram-negative bacteria. [PDF]

Appl Microbiol Biotechnol
Wongsombat C, Mhuantong W, Kongsee J, Pruksatrakul T, Srichomthong K, Charoenyingcharoen P, Uawisetwathana U, Yukphan P, Vichai V, Pistorius D, Buntin K, Aroonsri A.   +11 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The association of Tai Chi exercise with the methylation levels of the IL20 promoter. [PDF]

Front Sports Act Living
Chiang CH, Nfor ON, Chen LY, Wu MC, Chen YC, Jan CF, Lu WY, Liaw YP.   +7 more
europepmc   +1 more source