Results 181 to 190 of about 1,653,454 (343)

Fluoridated Water Supply and Promotion of Oral Health in Children of Low Socioeconomic Status- A Cross-Section Study [PDF]

, 2015
Cruvinel VR, Gravina DB, Peruchi CM, Bezerra Ac, Toledo Oa   +4 more
openalex   +1 more source

Analysis of Political Documents and Recommendations in Terms of Physical Activity Promotion for People with (Intellectual) Disabilities. [PDF]

Healthcare (Basel)
Neumeister S, Kreinbucher-Bekerle C.
europepmc   +1 more source

Quantifying the promotion of Cu catalysts by ZnO for methanol synthesis

Science, 2016
Sebastian Kuld, Max Thorhauge, H. Falsig, C. Elkjær, S. Helveg, I. Chorkendorff, J. Sehested   +6 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

How to distinguish promotion, prevention, and treatment trials in public mental health: development and validation of the VErona-LUgano Tool (VELUT). [PDF]

Epidemiol Psychiatr Sci
Purgato M, Albanese E, Gross AL, Annoni AM, Acarturk C, Cadorin C, Jordans MJD, Lund C, Papola D, Prina E, Sijbrandij M, Silva M, Tedeschi F, Tol WA, Barbui C.   +14 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Abrogation of aberrant glycolytic interactions eliminates senescent cells and alleviates aging-related dysfunctions. [PDF]

Signal Transduct Target Ther
Mikawa T, Kameda M, Ikari S, Shibata E, Liu S, Miyagawa S, Ono K, Ito T, Yoshizawa A, Sugimoto M, Shibuya S, Shimizu T, Almunia J, Ogiso N, Revêchon G, Palazzo A, Bernard D, Kanda H, Soga T, Takubo K, Morioka S, Sasaki J, Sasaki T, Itamoto A, Fujii T, Seno H, Inagaki N, Kondoh H.   +27 more
europepmc   +1 more source

Immune cell promotion of metastasis

Nature reviews. Immunology, 2015
T. Kitamura, Binzhi Qian, J. Pollard
semanticscholar   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Does social media promotion influence citation counts? A long-term follow-up to a randomised trial in a general neurosurgical journal. [PDF]

Neurosurg Rev
Schmidt AQ, Theiler S, Fariña Nuñez MT, El-Hajj VG, Vieli M, Battilana B, Alamri A, Rabiei K, Lippa L, Karekezi C, Kolias A, Serra C, Regli L, Mathiesen T, Staartjes VE.   +14 more
europepmc   +1 more source